2-[2-(2-Aminoethoxy)ethoxy]acetic Acid (BAT-006212)

H2N-PEG2-CH2COOH belongs to a polyethylene glycol (PEG) linker covalently bound to E3 Ligase binding group (E3LB) and protein binding group (PB). H2N-PEG2-CH2COOH is a PEG derivative containing an amino group with a terminal carboxylic acid. The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The terminal carboxylic acid can be reacted with primary amine groups in the presence of activators (e.g. EDC, or DCC) to form a stable amide bond. PEG Linkers may be useful in the development of antibody drug conjugates and PROTACs.

Category
Functional Peptides
Catalog number
BAT-006212
CAS number
134978-97-5
Molecular Formula
C6H13NO4
Molecular Weight
163.17
2-[2-(2-Aminoethoxy)ethoxy]acetic Acid
Ordering Information
Catalog Number Size Price Stock Quantity
BAT-006212 1 g $168 In stock
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Synonyms
Amino-PEG2-CH2CO2H
Related CAS
删除
Purity
98%
Solubility
10 mM in DMSO
InChI
InChI=1S/C6H13NO4/c7-1-2-10-3-4-11-5-6(8)9/h1-5,7H2,(H,8,9)
InChI Key
RUVRGYVESPRHSZ-UHFFFAOYSA-N
Canonical SMILES
C(COCCOCC(=O)O)N
Bio Calculators
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