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2-(2,6-Dioxo-3-piperidinyl)-4-hydroxyisoindoline-1,3-dione

* Please kindly note that our products are not to be used for therapeutic purposes and cannot be sold to patients.

Thalidomide-OH is a ligand for E3 ligase used in PROTAC technology.

Category

Peptide Synthesis Reagents

Catalog number

BAT-006491

CAS number

5054-59-1

Molecular Formula

C13H10N2O5

Molecular Weight

274.23

2-(2,6-Dioxo-3-piperidinyl)-4-hydroxyisoindoline-1,3-dione

Specification

IUPAC Name

2-(2,6-dioxopiperidin-3-yl)-4-hydroxyisoindole-1,3-dione

Synonyms

4-Hydroxy thalidomide; E3 ligase Ligand 2; Thalidomide-4-OH; 4-Hydroxy thalidomide, (+/-)-; 3-Hydroxythalidomide; 4-Hydroxy-thalidomide; α-(3-Hydroxy-phthalimido)-glutarimid; 2-(2,6-dioxopiperidin-3-yl)-4-hydroxyisoindoline-1,3-dione; 2-(2,6-dioxo-3-piperidinyl)-4-hydroxy-1H-isoindole-1,3(2H)-dione

Appearance

White to off-white solid

Purity

> 95 %

Density

1.611±0.06 g/cm³ (Predicted)

Melting Point

273-282 ℃

Boiling Point

568.3±45.0 ℃ (Predicted)

Storage

4 ℃, stored under nitrogen
*In solvent : -80 ℃, 6 months; -20 ℃, 1 month (stored under nitrogen)