3-(1-Naphthyl)-DL-alanine
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3-(1-Naphthyl)-DL-alanine

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Category
DL-Amino Acids
Catalog number
BAT-007798
CAS number
28095-56-9
Molecular Formula
C13H13NO2
Molecular Weight
215.25
3-(1-Naphthyl)-DL-alanine
IUPAC Name
2-amino-3-naphthalen-1-ylpropanoic acid
Synonyms
DL-3-Ala(1-naphthyl)-OH; 2-Amino-3-naphthalen-1-yl-propionic acid; H-DL-1-NAL-OH; 3-(1-Naphthyl)alanine; DL-3-(1-NAPHTHYL)ALANINE; H-D-1-Nal-OH; 2-amino-3-(1-naphthyl)propanoic acid; 2-AMINO-3-NAPHTHALEN-1-YL-PROPIONIC ACID; 1-Naphthylalanine; alphanaphthylalanine; naphtylalanine; D,L-beta-(1-Naphthyl)alanine; H DL 1 NAL OH
Appearance
Off-white powder
Purity
≥ 98% (HPLC)
Density
1.254 g/cm3 (Predicted)
Melting Point
> 196 °C (dec.)
Boiling Point
412.3±33.0 °C (Predicted)
Storage
Store at 2-8 °C
InChI
InChI=1S/C13H13NO2/c14-12(13(15)16)8-10-6-3-5-9-4-1-2-7-11(9)10/h1-7,12H,8,14H2,(H,15,16)
InChI Key
OFYAYGJCPXRNBL-UHFFFAOYSA-N
Canonical SMILES
C1=CC=C2C(=C1)C=CC=C2CC(C(=O)O)N

3-(1-Naphthyl)-DL-alanine, a synthetic amino acid boasting unique properties, has diverse applications across various disciplines. Delve into the key applications with a high degree of perplexity and burstiness:

Protein Engineering: In the realm of protein engineering, the utilization of 3-(1-Naphthyl)-DL-alanine revolutionizes the introduction of non-standard amino acids into proteins. By integrating this synthetic amino acid, researchers embark on a journey to explore protein folding, stability, and functionality, ultimately shaping the design of proteins endowed with novel characteristics and heightened performance for a myriad of biotechnological pursuits.

Biochemical Assays: Positioned at the forefront of biochemical research, 3-(1-Naphthyl)-DL-alanine emerges as a pivotal substrate or probe in enzymatic assays. Its distinctive attributes pave the way for its deployment in fluorescence-based assays, enabling the meticulous monitoring of enzyme activity and kinetics. These assays serve as indispensable tools in the realms of drug discovery and the thorough unraveling of intricate enzyme mechanisms.

Drug Development: Embracing the potential of 3-(1-Naphthyl)-DL-alanine as a frontrunner in drug development heralds a new era in therapeutic innovation. The exceptional structural features of this compound serve as a beacon for designing molecules that form precise interactions with biological targets, including receptors and enzymes. This groundbreaking approach holds the promise of ushering in a wave of new therapeutic agents characterized by enhanced efficacy and selective targeting, reshaping the landscape of pharmaceutical advancement.

Structural Biology: The integration of 3-(1-Naphthyl)-DL-alanine into peptides and proteins stands as a cornerstone in structural biology investigations. This amino acid serves as a beacon, guiding researchers in labeling proteins for advanced methodologies like NMR or X-ray crystallography. Such strategic utilization facilitates the unraveling of intricate protein structures, providing unprecedented insights into dynamic processes and intricate molecular interactions, propelling structural biology studies to new heights of understanding and discovery.

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