3-Amino-2,6-piperidinedione hydrochloride
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3-Amino-2,6-piperidinedione hydrochloride

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3-Aminopiperidine-2,6-dione hydrochloride is a reagent for preparing lenalidomide that can induce ubiquitination and degradation of CK1α in del(5q) MDS. It can also be used to prepare phthalimide conjugates that can promote ligand-dependent target protein degradation.

Category
Peptide Synthesis Reagents
Catalog number
BAT-006301
CAS number
24666-56-6
Molecular Formula
C5H9ClN2O2
Molecular Weight
164.59
3-Amino-2,6-piperidinedione hydrochloride
IUPAC Name
3-aminopiperidine-2,6-dione;hydrochloride
Synonyms
3-Amino-2,6-piperidinedione Monohydrochloride; 2-Amino-glutarimide Hydrochloride; 3-Amino-2,6-dioxopiperidine Hydrochloride; 3-Aminopiperidine-2,6-dione Monohydrochloride; DL-Glutamic Acid Imide Hydrochloride; Glutamimide Hydrochloride; 2,6-dioxopiperidine-3-ammonium chloride; Glutamic acid imide hydrochloride; Glutamic acid imide-DL-hydrochloride; ACMC-20a23n; (+-)-3-Amino-2,6-piperidinedione monohydrochloride; AMPD00004; 3-Aminopiperidine-2,6-dione, HCl
Related CAS
2686-86-4 2353-44-8 (free base)
Appearance
White to off-white solid
Purity
> 99 %
Melting Point
> 208 °C (dec.)
Boiling Point
334.5 °C at 760 mmHg
Storage
2-8 °C
Solubility
Soluble in Water; Slightly soluble in DMSO (Heated); Sparingly soluble in Methanol (Sonicated)
InChI
InChI=1S/C5H8N2O2.ClH/c6-3-1-2-4(8)7-5(3)9;/h3H,1-2,6H2,(H,7,8,9);1H
InChI Key
YCPULGHBTPQLRH-UHFFFAOYSA-N
Canonical SMILES
C1CC(=O)NC(=O)C1N.Cl
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