β-(3-Pyridyl)-L-alanine
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β-(3-Pyridyl)-L-alanine

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Category
L-Amino Acids
Catalog number
BAT-007521
CAS number
64090-98-8
Molecular Formula
C8H10N2O2
Molecular Weight
166.18
β-(3-Pyridyl)-L-alanine
IUPAC Name
(2S)-2-amino-3-pyridin-3-ylpropanoic acid
Alternative CAS
28105-69-3
Synonyms
H-Ala(3-Pyri)-OH; H-Ala(3-Pyridyl)-OH; (S)-2-Amino-3-(pyridin-3-yl)propanoic acid; L-3-Pyridylalanine; 3-(3-Pyridyl)-L-alanine; H-3-PAL-OH; 3-(3-Pyridyl)alanine; 3-Pyridin-3-yl-L-alanine; 3'-PYRIDYL-L-ALA; (2S)-2-amino-3-(pyridin-3-yl)propanoic acid
Appearance
Off-white powder
Purity
≥ 99% (HPLC)
Density
1.271±0.06 g/cm3 (Predicted)
Melting Point
248-252 °C
Boiling Point
344.4±32.0 °C (Predicted)
Storage
Store at 2-8 °C
InChI
InChI=1S/C8H10N2O2/c9-7(8(11)12)4-6-2-1-3-10-5-6/h1-3,5,7H,4,9H2,(H,11,12)/t7-/m0/s1
InChI Key
DFZVZEMNPGABKO-ZETCQYMHSA-N
Canonical SMILES
C1=CC(=CN=C1)CC(C(=O)O)N

β-(3-Pyridyl)-L-alanine is a notable compound with several important applications in bioscience and related industries. Here are some key applications of β-(3-Pyridyl)-L-alanine:

Neuroscience Research: β-(3-Pyridyl)-L-alanine has been used in neuroscience research to study its effects on the nervous system and its potential neuroprotective properties. It serves as a valuable tool for investigating mechanisms underlying neurodegenerative diseases. Researchers can examine its interactions with neural pathways and receptors to better understand its therapeutic potential.

Biochemical Studies: In biochemical studies, β-(3-Pyridyl)-L-alanine is employed to explore enzyme-substrate interactions and metabolic pathways. This compound can act as a substrate or inhibitor in various enzymatic reactions, providing insights into enzyme kinetics and function. These studies are crucial for developing new pharmaceutical agents and understanding metabolic disorders.

Pharmaceutical Development: β-(3-Pyridyl)-L-alanine is investigated for its potential therapeutic applications, particularly in developing drugs targeting specific diseases. Its structure and biological activity can be optimized to design new compounds with enhanced efficacy and reduced side effects. This research contributes to the discovery of novel drug candidates.

Chemical Synthesis: β-(3-Pyridyl)-L-alanine is utilized as an intermediate in the synthesis of more complex chemical entities. Its unique structure makes it a valuable building block for constructing diverse molecules in medicinal chemistry. This enables the creation of new compounds with potential applications in various fields, including healthcare and materials science.

1.Comparative effects of DL, D and L-3-pyridylalanine on serotonin concentration and tryptophan-serotonin metabolizing enzymes.
Shimeno H, Fukumoto Y, Fuji M, Nagamatsu A. Chem Pharm Bull (Tokyo). 1984 Sep;32(9):3620-5.
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