β-(3-Thienyl)-D-alanine
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β-(3-Thienyl)-D-alanine

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Category
D-Amino Acids
Catalog number
BAT-005810
CAS number
152612-26-5
Molecular Formula
C7H9NO2S
Molecular Weight
171.20
β-(3-Thienyl)-D-alanine
IUPAC Name
(2R)-2-amino-3-thiophen-3-ylpropanoic acid
Synonyms
3-D-Ala(3-thienyl)-OH
Appearance
White powder
Purity
≥ 99% (HPLC, Chiral purity)
Density
1.349g/cm3
Storage
Store at 2-8°C
InChI
InChI=1S/C7H9NO2S/c8-6(7(9)10)3-5-1-2-11-4-5/h1-2,4,6H,3,8H2,(H,9,10)/t6-/m1/s1
InChI Key
VOIZSAUUYAGTMS-ZCFIWIBFSA-N
Canonical SMILES
C1=CSC=C1CC(C(=O)O)N

β-(3-Thienyl)-D-alanine, a unique amino acid derivative, finds diverse applications in chemical, pharmaceutical, and biological research. Here are the key applications of β-(3-Thienyl)-D-alanine presented with high perplexity and burstiness:

Drug Development: Playing a pivotal role in drug innovation, β-(3-Thienyl)-D-alanine's distinct structural characteristics make it valuable for crafting novel therapeutic agents. Incorporating this compound into peptide drugs enhances their stability, bioavailability, and binding affinity to target receptors. This strategic integration facilitates the design of drugs with heightened efficacy and diminished side effects, ushering in a new era of pharmaceutical advancement.

Biocatalysis: Within the dynamic realm of biocatalysis, β-(3-Thienyl)-D-alanine emerges as a versatile player, serving as both a substrate and inhibitor in enzyme-catalyzed reactions. Researchers leverage this compound to probe enzyme specificity and unravel reaction mechanisms involving amino acids. This deeper insight fuels the development of innovative biocatalysts for industrial applications, propelling the field towards groundbreaking discoveries.

Chemical Probes: Stepping into the domain of chemical probes, β-(3-Thienyl)-D-alanine acts as a valuable tool for dissecting protein functions and interactions. Integrating this compound into peptides and proteins aids in pinpointing binding sites, structural motifs, and biological activities. This investigative approach is instrumental in decoding the intricate roles of proteins within complex biological systems, shedding light on the fundamental workings of life at a molecular level.

Synthetic Biology: In the avant-garde realm of synthetic biology, β-(3-Thienyl)-D-alanine plays a pivotal role in engineering novel biosynthetic pathways. By integrating this amino acid into metabolic pathways, synthetic biologists engineer organisms capable of producing new biomolecules with tailored properties. This transformative innovation fuels advancements in biotechnology, facilitating the production of pharmaceuticals, biofuels, and biomaterials with unprecedented precision and efficiency.

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