(4-Methylphenylsulfonylamino)acetic acid

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(4-Methylphenylsulfonylamino)acetic acid
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(4-Methylphenylsulfonylamino)acetic acid is a sulfonamide derivative used to synthesize metal complexes which potentially displays antibacterial activity.

Other Unnatural Amino Acids
Catalog number
CAS number
Molecular Formula
Molecular Weight
(4-Methylphenylsulfonylamino)acetic acid
Tos-Gly-OH; N-p-Tosylglycine; 2-(4-Methylphenylsulfonamido)acetic acid; N-P-TOSYLGLYCINE; 2-[(4-methylphenyl)sulfonylamino]acetic acid; N-(p-Toluenesulfonyl)glycine; N-Tosylglycine; N-[(4-methylphenyl)sulfonyl]glycine; N-4-Tosylglycine; N-(toluene-4-sulfonyl)-glycine; Tos Gly OH
White to off-white powder
≥ 98% (HPLC)
1.369±0.06 g/cm3 (Predicted)
Melting Point
147-149 °C
Boiling Point
430.0±55.0 °C (Predicted)
Store at 2-8 °C
1. Acetic Acid Use in Chronic Wound Healing: A Multiple Case Series
Qiuyun Chen, Kehua Zhou J Wound Ostomy Continence Nurs. 2022 May-Jun;49(3):286-289. doi: 10.1097/WON.0000000000000863. Epub 2022 Mar 7.
Background: Acetic acid is bacteriostatic or bactericidal to many gram-negative and gram-positive microorganisms, especially Pseudomonas. Nevertheless, it has also been found to possess cytotoxic effects in concentrations as low as 0.25% inhibiting the epithelialization process during wound healing. Cases: In this multiple case series, we present 2 cases of chronic traumatic leg wounds treated with gauze moistened with acetic acid (0.25%), which were covered with a securing dressing and compression stockinet. Both patients were told to apply gauze moistened with acetic acid (0.25%) twice daily. In both cases, the wound progressed to blue-green drainage and wet yellow slough tissue to near-complete beefy granulation tissue. At this point, acetic acid was replaced with collagen or petrolatum dressing until complete wound closure was achieved. The treatment of these wounds illustrated successful use of acetic acid for chronic wound care. Conclusion: Our experience with these cases suggests that appearance of blue-green wound drainage and wet yellow slough tissue is a reasonable indication for the use of gauze moistened with acetic acid (0.25%). Further research is needed to test the efficacy of these principles in guiding acetic acid use in wound care.
2. [Unhealthy weight loss. Erosion by apple cider vinegar]
D L Gambon, H S Brand, E C I Veerman Ned Tijdschr Tandheelkd. 2012 Dec;119(12):589-91. doi: 10.5177/ntvt.2012.12.12192.
Erosive tooth wear was diagnosed in the dentition of a 15-year-old girl with a Moroccan background. After an anamnesis, extensive analysis of possible risk factors and a study of the pattern of erosion, it was concluded that the erosive tooth wear was induced by daily consumption of a glass of apple cider vinegar Further investigation revealed that in North-African culture, women have used apple cider vinegar to achieve weight loss for generations. Bodybuilders are also known to make use of this method of weight reduction.
3. Fruits Vinegar: Quality Characteristics, Phytochemistry, and Functionality
Driss Ousaaid, Hamza Mechchate, Hassan Laaroussi, Christophe Hano, Meryem Bakour, Asmae El Ghouizi, Raffaele Conte, Badiaa Lyoussi, Ilham El Arabi Molecules. 2021 Dec 30;27(1):222. doi: 10.3390/molecules27010222.
The popularity of fruits vinegar (FsV) has been increased recently as a healthy drink wealthy in bioactive compounds that provide several beneficial properties. This review was designed in the frame of valorization of fruits vinegar as a by-product with high value added by providing overall information on its biochemical constituents and beneficial potencies. It contains a cocktail of bioactive ingredients including polyphenolic acids, organic acids, tetramethylperazine, and melanoidins. Acetic acid is the most abundant organic acid and chlorogenic acid is the major phenol in apple vinegar. The administration of fruits vinegar could prevent diabetes, hypercholesterolemia, oxidative stress, cancer, and boost immunity as well as provide a remarkable antioxidant ability. The production techniques influence the quality of vinegar, and consequently, its health benefits.

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