β-(5-Bromo-2-thienyl)-L-alanine
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β-(5-Bromo-2-thienyl)-L-alanine

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β-(5-Bromo-2-thienyl)-L-alanine is used as a building block to synthesize fibrinogen receptor antagonists.

Category
L-Amino Acids
Catalog number
BAT-007526
CAS number
154593-58-5
Molecular Formula
C7H8BrNO2S
Molecular Weight
250.11
β-(5-Bromo-2-thienyl)-L-alanine
IUPAC Name
(2S)-2-amino-3-(5-bromothiophen-2-yl)propanoic acid
Synonyms
H-Ala{2-Thienyl(5-Br)}-OH; H-Thi(2)(5-Br)-OH; L-2-(5-Bromothienyl)alanine; (S)-2-Amino-3-(5-bromothiophen-2-yl)propanoic acid; 3-(5-Bromothiophen-2-Yl)-L-Alanine; 3-(5-Bromo-2-thienyl)alanine; beta-(5-Bromo-2-thienyl)-L-alanine; L-α-(5-Bromothienyl)alanine; L-Thi(5-Br)-OH
Appearance
White powder
Purity
≥ 99% (HPLC)
Density
1.747±0.06 g/cm3 (Predicted)
Melting Point
262 °C
Boiling Point
368.5±42.0 °C (Predicted)
Storage
Store at 2-8 °C
InChI
InChI=1S/C7H8BrNO2S/c8-6-2-1-4(12-6)3-5(9)7(10)11/h1-2,5H,3,9H2,(H,10,11)/t5-/m0/s1
InChI Key
LKORPMMOJAJYLC-YFKPBYRVSA-N
Canonical SMILES
C1=C(SC(=C1)Br)CC(C(=O)O)N

β-(5-Bromo-2-thienyl)-L-alanine, a derivative of alanine, exhibits diverse applications in biochemical research and pharmaceutical development. Here are the key applications presented with high perplexity and burstiness:

Enzyme Inhibition Studies: Delving into enzyme kinetics and inhibition, β-(5-Bromo-2-thienyl)-L-alanine serves as both a substrate and inhibitor, allowing researchers to scrutinize the intricate interactions between enzymes and various molecules. This exploration can catalyze the creation of innovative enzyme inhibitors with significant therapeutic potential, paving the way for novel treatment approaches.

Protein Structure and Function Analysis: Playing a pivotal role in unraveling protein intricacies, this compound aids in studying the structure and function of proteins. By integrating the modified alanine into proteins, researchers can elucidate how structural alterations impact protein activity, shedding light on crucial protein regions essential for their biological functionality.

Drug Design and Development: Driving advances in pharmaceutical innovation, β-(5-Bromo-2-thienyl)-L-alanine contributes to the design of new drugs by acting as a lead compound or template, streamlining the synthesis of novel drug candidates. Scientists can examine its interactions with biological targets to fine-tune the efficacy and safety profiles of emerging therapeutic agents, pushing the boundaries of drug discovery.

Metabolic Pathway Studies: In the realm of metabolic pathway research, this compound plays a pivotal role in exploring amino acid metabolism and associated pathways. Integrating the modified alanine into metabolic investigations enables scientists to monitor its cellular processing, offering crucial insights into metabolic diseases and facilitating the development of targeted therapeutic interventions to combat these conditions effectively.

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