A(Boc) Acetic acid
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A(Boc) Acetic acid

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A nucleobase for PNA synthesis.

Catalog number
CAS number
Molecular Formula
Molecular Weight
A(Boc) Acetic acid
2-[6-[(2-methylpropan-2-yl)oxycarbonylamino]purin-9-yl]acetic acid
2-(6-((Tert-Butoxycarbonyl)amino)-9H-purin-9-yl)acetic acid; 6-(tert-Butoxycarbonylamino)-9H-purine-9-acetic acid; (N6-Boc-N9-adeninyl)acetic acid; N6-Boc-adenosin-9-yl acetic acid
White to Off-white Powder
1.5±0.1 g/cm3
-20°C for long term storage
InChI Key
Canonical SMILES
1. 2-[(tert-But-oxy-carbonyl-amino)-oxy]acetic acid
Jing-Yu Zhang, Yan Tong, Shengqi Wang Acta Crystallogr Sect E Struct Rep Online. 2011 Sep 1;67(Pt 9):o2324. doi: 10.1107/S1600536811031990. Epub 2011 Aug 11.
The title compound, C(7)H(13)NO(5), was prepared by the condensation of O-(carb-oxy-meth-yl)hydroxyl-amine and (Boc)(2)O (Boc = but-oxy-carbon-yl).In the crystal, mol-ecules are linked by weak inter-molecular N-H⋯O hydrogen bonds.
2. Acid-Facilitated Debenzylation of N-Boc, N-Benzyl Double Protected 2-Aminopyridinomethylpyrrolidine Derivatives
Haitao Ji, Qing Jing, Jinwen Huang, Richard B Silverman Tetrahedron. 2012 Feb 4;68(5):1359-1366. doi: 10.1016/j.tet.2011.12.013. Epub 2011 Dec 13.
2-Aminopyridinomethyl pyrrolidines represent a class of highly potent and selective neuronal nitric oxide synthase inhibitors. Conditions for a Mitsunobu reaction of a naphthol and a hindered secondary alcohol were optimized to give good to excellent yields. A key step in the synthesis of these inhibitors is the deprotection of the benzyl group from the N-Boc and N-Bn double protected 2-aminopyridine ring at a late stage of the synthesis, which has been proven difficult in our previous syntheses. Acetic acid was found to facilitate the N-Bn deprotection.
3. Synthesis of a plasmonic AgCl and oxygen-rich Bi24O31Cl10 composite heterogeneous catalyst for enhanced degradation of tetracycline and 2,4-dichlorophenoxy acetic acid
Dorcas Adenuga, Sifiso Skosana, Shepherd Tichapondwa, Evans Chirwa RSC Adv. 2021 Nov 16;11(58):36760-36768. doi: 10.1039/d1ra06855e. eCollection 2021 Nov 10.
In this study, a AgCl/Bi24O31Cl10 composite heterostructure was constructed. Varying ratios of AgCl nanoparticles were immobilised onto the Bi24O31Cl10 rod-like structure. The physical and optical properties of the synthesised catalysts were characterised using a range of techniques. The photocatalytic activity of the catalysts was investigated by the degradation of 2,4-dichlorophenoxy acetic acid (2,4-D) and tetracycline (TC) under visible light irradiation. The performance of the composite photocatalysts was 18 and 3.4 times better in 2-4,D and TC photodegradation when compared to Bi24O31Cl10 alone. The improved photocatalytic performance was due to the surface plasmon resonance (SPR) effects of the Ag nanoparticles deposited on the surface of the Xwt%AgCl/BOC thereby improving the separation of the electron-hole pair. The effects of the initial contaminant concentration, pH, photocatalyst loading were investigated. Trapping experiments were also carried out to deduce the reactive species responsible for the degradation process and a preliminary mechanism of degradation was proposed. Successful mineralisation of 2,4-D and TC at 65% and 63% efficiency was also measured after 24 h and the potential for reusability of the as-synthesised photocatalyst was established. This work reports a promising heterogeneous photocatalyst for the removal of pollutants such as TC and 2,4-D from wastewater.
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