Abz-LFK(Dnp)-OH trifluoroacetate salt
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Abz-LFK(Dnp)-OH trifluoroacetate salt

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Abz-LFK(Dnp)-OH trifluoroacetate salt is an angiotensin-converting enzyme (ACE) fluorescent peptide substrate that binds specifically to the C domain of ACE. It has been used to investigate the development of novel antibacterial calixarene derivatives, as well as the efficacy and toxicity of antimicrobial peptide M33 as a possible antimicrobial agent for lung infections and sepsis.

Category
Others
Catalog number
BAT-016024
CAS number
1217437-31-4
Molecular Formula
C34H41N7O9.C2HF3O2
Molecular Weight
805.76
Abz-LFK(Dnp)-OH trifluoroacetate salt
IUPAC Name
(2S)-2-[[(2S)-2-[[(2S)-2-[(2-aminobenzoyl)amino]-4-methylpentanoyl]amino]-3-phenylpropanoyl]amino]-6-(2,4-dinitroanilino)hexanoic acid;2,2,2-trifluoroacetic acid
Synonyms
O-Aminobenzoic acid-Leu-Phe-Lys(DNP)-OH trifluoroacetate salt; Abz-Leu-Phe-Lys-DNP trifluoroacetate salt; (2-aminobenzoyl)-L-leucyl-L-phenylalanyl-N6-(2,4-dinitrophenyl)-L-lysine trifluoroacetic acid; N-(2-Aminobenzoyl)-L-leucyl-L-phenylalanyl-N6-(2,4-dinitrophenyl)-L-lysine trifluoroacetate (1:1); L-Lysine, N-(2-aminobenzoyl)-L-leucyl-L-phenylalanyl-N6-(2,4-dinitrophenyl)-, compd. with 2,2,2-trifluoroacetic acid (1:1); (2S)-2-[[(2S)-2-([(2S)-2-[(2-Aminobenzoyl)amino]-4-methylpentanoyl]amino)-3-phenylpropanoyl]amino]-6-(2,4-dinitroanilino)hexanoic acid trifluoroacetate
Related CAS
1217437-30-3 (free base)
Purity
≥97% by HPLC
Sequence
H-2Abz-Leu-Phe-Lys(Dnp)-OH.TFA
Storage
Store at 2-8°C
InChI
InChI=1S/C34H41N7O9.C2HF3O2/c1-21(2)18-28(38-31(42)24-12-6-7-13-25(24)35)32(43)39-29(19-22-10-4-3-5-11-22)33(44)37-27(34(45)46)14-8-9-17-36-26-16-15-23(40(47)48)20-30(26)41(49)50;3-2(4,5)1(6)7/h3-7,10-13,15-16,20-21,27-29,36H,8-9,14,17-19,35H2,1-2H3,(H,37,44)(H,38,42)(H,39,43)(H,45,46);(H,6,7)/t27-,28-,29-;/m0./s1
InChI Key
BAXBDLHYKKDHEJ-BJRQXHFHSA-N
Canonical SMILES
O=C(O)C(NC(=O)C(NC(=O)C(NC(=O)C=1C=CC=CC1N)CC(C)C)CC=2C=CC=CC2)CCCCNC3=CC=C(C=C3N(=O)=O)N(=O)=O.O=C(O)C(F)(F)F
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