Ac-Arg-NH2
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Ac-Arg-NH2

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Category
L-Amino Acids
Catalog number
BAT-015833
CAS number
64365-27-1
Molecular Formula
C8H17N5O2
Molecular Weight
215.25
Ac-Arg-NH2
IUPAC Name
(2S)-2-acetamido-5-(diaminomethylideneamino)pentanamide
Synonyms
Ac-Arg-Nh2 Salt; N-acetylarginamide; N-alpha-Acetyl-L-arginine amide; (S)-2-acetamido-5-guanidinopentanamide
Density
1.38±0.1 g/cm3
InChI
InChI=1S/C8H17N5O2/c1-5(14)13-6(7(9)15)3-2-4-12-8(10)11/h6H,2-4H2,1H3,(H2,9,15)(H,13,14)(H4,10,11,12)/t6-/m0/s1
InChI Key
ZWAIIHKSWHGLFY-LURJTMIESA-N
Canonical SMILES
CC(=O)NC(CCCN=C(N)N)C(=O)N

Ac-Arg-NH2, also known as N-α-Acetyl-L-argininamide, a versatile peptide derivative, finds diverse applications in biochemical and biotechnological fields. Delve into the intricate world of Ac-Arg-NH2 with these four high-perplexity, bursty applications:

Biochemical Studies: Ac-Arg-NH2 emerges as a pivotal tool in biochemical studies, unraveling the intricate roles of arginine residues within protein structures. By incorporating this peptide into experimental setups, researchers dive deep into how arginine modifications impact enzyme activities and protein interactions. This exploration sheds light on protein biochemistry, setting the stage for targeted therapeutic interventions directed at specific proteins.

Pharmaceutical Development: Spearheading pharmaceutical breakthroughs, Ac-Arg-NH2 forms a cornerstone in the synthesis of peptide-based drugs. Its integration into peptide sequences enhances drug stability and efficacy by conferring resistance to enzymatic degradation. This unique attribute positions it as a valuable asset in formulating and refining peptide therapeutics across various disease spectra, pushing the boundaries of pharmaceutical innovation.

Cell Culture: In the realm of cell culture applications, Ac-Arg-NH2 acts as a vital enhancer, bolstering cell growth and viability in culture media. Providing an additional source of arginine—a pivotal element for protein synthesis and cellular metabolism—this peptide elevates the performance of cell culture systems, especially in biologics and therapeutic protein production. It nurtures an environment conducive to cellular flourishing, fostering optimal conditions for cellular growth.

Protein Engineering: Unveiling its transformative potential in protein engineering, Ac-Arg-NH2 empowers the infusion of specific functional groups into proteins. Through strategic protein alterations with this peptide, researchers fine-tune critical properties like binding affinity, solubility, and stability. This tailored development of proteins enriches the landscape of industrial, diagnostic, and therapeutic applications, marking a significant stride in protein engineering endeavors.

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