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Ac-DNLD-CHO

Name: Ac-DNLD-CHO
Brand: BOC Sciences
Rating: 5 (1 reviews)

* Please kindly note that our products are not to be used for therapeutic purposes and cannot be sold to patients.

Ac-DNLD-CHO is a Caspase-3/7 inhibitor with IC50 of 3.2 nM and 22.6 nM, respectively. Ac-DNLD-CHO may be an attractive lead compound to generate novel effective non-peptidic pharmaceuticals for caspase-mediated apoptosis diseases, such as neurodegenerative disorders and viral infection diseases.

Category

Peptide Inhibitors

Catalog number

BAT-016764

CAS number

775289-20-8

Molecular Formula

C20H31N5O10

Molecular Weight

501.49

Specification

IUPAC Name

(3S)-3-acetamido-4-[[(2S)-4-amino-1-[[(2S)-1-[[(2S)-1-carboxy-3-oxopropan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-1,4-dioxobutan-2-yl]amino]-4-oxobutanoic acid

Synonyms

N-acetyl-Asp-Asn-Leu-Asp-aldehyde; Ac-Asp-Asn-Leu-Asp-al; Caspase-3/7 Inhibitor II

Density

1.3±0.1 g/cm3

Boiling Point

1034.0±65.0 °C at 760 mmHg

Sequence

Ac-Asp-Asn-Leu-Asp-al

Storage

Store at -20 °C

InChI

InChI=1S/C20H31N5O10/c1-9(2)4-12(18(33)23-11(8-26)5-16(29)30)24-19(34)13(6-15(21)28)25-20(35)14(7-17(31)32)22-10(3)27/h8-9,11-14H,4-7H2,1-3H3,(H2,21,28)(H,22,27)(H,23,33)(H,24,34)(H,25,35)(H,29,30)(H,31,32)/t11-,12-,13-,14-/m0/s1

InChI Key

XZGUQURUQBIHMG-XUXIUFHCSA-N

Canonical SMILES

CC(C)C[C@@H](C(=O)N[C@@H](CC(=O)O)C=O)NC(=O)[C@H](CC(=O)N)NC(=O)[C@H](CC(=O)O)NC(=O)C