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Ac-Gly-Pro-AFC
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Ac-Gly-Pro-AFC

* Please kindly note that our products are not to be used for therapeutic purposes and cannot be sold to patients.

Ac-Gly-Pro-AFC is a specific substrate for the endopeptidase activity of fibroblast activation protein (FAP) (Km = 330±30 μM; kcat = 7.7±0.2 s-1).

Category
Others
Catalog number
BAT-014564
CAS number
886993-02-8
Molecular Formula
C19H18F3N3O5
Molecular Weight
425.36
IUPAC Name
(2S)-1-(2-acetamidoacetyl)-N-[2-oxo-4-(trifluoromethyl)chromen-7-yl]pyrrolidine-2-carboxamide
Synonyms
Ac-GP-AFC; N-Acetylglycyl-N-[2-oxo-4-(trifluoromethyl)-2H-1-benzopyran-7-yl]-L-prolinamide; L-Prolinamide, N-acetylglycyl-N-[2-oxo-4-(trifluoromethyl)-2H-1-benzopyran-7-yl]-; N-Acetylglycyl-N-[2-oxo-4-(trifluoromethyl)-2H-chromen-7-yl]-L-prolinamide; (S)-1-(2-acetamidoacetyl)-N-(2-oxo-4-(trifluoromethyl)-2H-chromen-7-yl)pyrrolidine-2-carboxamide
Appearance
Light Yellow Powder
Purity
≥95%
Density
1.480±0.06 g/cm3 (Predicted)
Boiling Point
689.9±55.0°C (Predicted)
Storage
Store at -20°C
Solubility
Soluble in Methanol
InChI
InChI=1S/C19H18F3N3O5/c1-10(26)23-9-16(27)25-6-2-3-14(25)18(29)24-11-4-5-12-13(19(20,21)22)8-17(28)30-15(12)7-11/h4-5,7-8,14H,2-3,6,9H2,1H3,(H,23,26)(H,24,29)/t14-/m0/s1
InChI Key
SKKLIRUAUNZTRY-AWEZNQCLSA-N
Canonical SMILES
CC(=O)NCC(=O)N1CCCC1C(=O)NC2=CC3=C(C=C2)C(=CC(=O)O3)C(F)(F)F
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