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Ac-IETD-AMC

Name: Ac-IETD-AMC
Brand: BOC Sciences
Rating: 5 (1 reviews)

* Please kindly note that our products are not to be used for therapeutic purposes and cannot be sold to patients.

Ac-IETD-AMC is a fluorogenic substrate for Procaspase-3 Cleaving Enzyme (Caspase-8/Caspase-6 and Granzyme B).

Category

Functional Peptides

Catalog number

BAT-016758

CAS number

348079-17-4

Molecular Formula

C31H41N5O12

Molecular Weight

675.68

Specification

IUPAC Name

(4S)-4-[[(2S,3S)-2-acetamido-3-methylpentanoyl]amino]-5-[[(2S,3R)-1-[[(2S)-3-carboxy-1-[(4-methyl-2-oxochromen-7-yl)amino]-1-oxopropan-2-yl]amino]-3-hydroxy-1-oxobutan-2-yl]amino]-5-oxopentanoic acid

Synonyms

Ac-Ile-Glu-Thr-Asp-AMC; Ac-Ile-Glu-Thr-Asp-MCA

Sequence

Ac-Ile-Glu-Thr-Asp-AMC

Storage

Store at -20 °C

InChI

InChI=1S/C31H41N5O12/c1-6-14(2)26(32-17(5)38)30(46)34-20(9-10-23(39)40)28(44)36-27(16(4)37)31(47)35-21(13-24(41)42)29(45)33-18-7-8-19-15(3)11-25(43)48-22(19)12-18/h7-8,11-12,14,16,20-21,26-27,37H,6,9-10,13H2,1-5H3,(H,32,38)(H,33,45)(H,34,46)(H,35,47)(H,36,44)(H,39,40)(H,41,42)/t14-,16+,20-,21-,26-,27-/m0/s1

InChI Key

ZYTCBVQZQSFKHQ-HGZCCCDHSA-N

Canonical SMILES

CC[C@H](C)[C@@H](C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(=O)O)C(=O)NC1=CC2=C(C=C1)C(=CC(=O)O2)C)NC(=O)C