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Acetyl-Amyloid β-Protein (1-6) amide

* Please kindly note that our products are not to be used for therapeutic purposes and cannot be sold to patients.

Experiments using sub-peptides of Aβ42 show that the epitope identified by antibody A8 is located in the 1-6 region of Aβ.

Category

Functional Peptides

Catalog number

BAT-014844

CAS number

903883-22-7

Molecular Formula

C35H50N12O11

Molecular Weight

814.85

Specification

IUPAC Name

(4S)-4-[[(2S)-2-[[(2S)-2-acetamido-3-carboxypropanoyl]amino]propanoyl]amino]-5-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-5-oxopentanoic acid

Synonyms

Ac-DAEFRH-NH2; L-Histidinamide, N-acetyl-L-α-aspartyl-L-alanyl-L-α-glutamyl-L-phenylalanyl-L-arginyl-; N-acetyl-L-alpha-aspartyl-L-alanyl-L-alpha-glutamyl-L-phenylalanyl-L-arginyl-L-histidinamide

Appearance

White Powder

Purity

≥95%

Sequence

Ac-Asp-Ala-Glu-Phe-Arg-His-NH2

Storage

Store at -20°C

Solubility

Soluble in DMSO, Water

InChI

InChI=1S/C35H50N12O11/c1-18(42-33(57)26(15-28(51)52)43-19(2)48)30(54)44-23(10-11-27(49)50)32(56)47-25(13-20-7-4-3-5-8-20)34(58)45-22(9-6-12-40-35(37)38)31(55)46-24(29(36)53)14-21-16-39-17-41-21/h3-5,7-8,16-18,22-26H,6,9-15H2,1-2H3,(H2,36,53)(H,39,41)(H,42,57)(H,43,48)(H,44,54)(H,45,58)(H,46,55)(H,47,56)(H,49,50)(H,51,52)(H4,37,38,40)/t18-,22-,23-,24-,25-,26-/m0/s1

InChI Key

GTHSRUQEDKNWPD-VVKHCXNMSA-N

Canonical SMILES

CC(C(=O)NC(CCC(=O)O)C(=O)NC(CC1=CC=CC=C1)C(=O)NC(CCCN=C(N)N)C(=O)NC(CC2=CN=CN2)C(=O)N)NC(=O)C(CC(=O)O)NC(=O)C