β-Alanine β-naphthylamide hydrobromide
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β-Alanine β-naphthylamide hydrobromide

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Category
β−Amino Acids
Catalog number
BAT-007611
CAS number
201985-01-5
Molecular Formula
C13H14N2O·HBr
Molecular Weight
295.27
β-Alanine β-naphthylamide hydrobromide
IUPAC Name
3-amino-N-naphthalen-2-ylpropanamide;hydrobromide
Synonyms
β-Ala-βNA HBr; Beta-alanine beta-naphthylamide hydrobromide; H-beta-Ala-betaNA HBr; 3-Amino-N-(naphthalen-2-yl)propanamide hydrobromide; H-beta-Ala-betaNA hydrobromide; H-beta-Ala-beta-naphthalene hydrobromide; J-013113; H beta Ala betaNA HBr
Related CAS
1283768-30-8 (hydrochloride)
Appearance
Light beige powder
Purity
≥ 99% (Assay by Elemental analysis, TLC)
Storage
Store at 2-8 °C
InChI
InChI=1S/C13H14N2O.BrH/c14-8-7-13(16)15-12-6-5-10-3-1-2-4-11(10)9-12;/h1-6,9H,7-8,14H2,(H,15,16);1H
InChI Key
NXOOSBFVJFJSAW-UHFFFAOYSA-N
Canonical SMILES
C1=CC=C2C=C(C=CC2=C1)NC(=O)CCN.Br

β-Alanine β-naphthylamide hydrobromide, a synthetic compound, finds extensive applications in biochemical and clinical research. Here are the key applications presented with high perplexity and burstiness:

Enzyme Activity Assays: Serving as a prevalent substrate for aminopeptidases in enzyme activity assays, β-Alanine β-naphthylamide hydrobromide undergoes hydrolysis by enzymes, yielding a detectable product that can be quantified spectrophotometrically. This indispensable application is crucial for evaluating enzymatic activity in diverse clinical and research scenarios, aiding in the identification of specific peptidases and their corresponding inhibitors.

Inhibitor Screening Studies: Researchers employ β-Alanine β-naphthylamide hydrobromide in screening assays to pinpoint potential inhibitors of aminopeptidases. By investigating the impact of various compounds on the hydrolysis of this substrate, scientists can unearth molecules with therapeutic potential. This iterative process is fundamental to drug development, especially in targeting diseases where aminopeptidases exert significant influence.

Biochemical Research: Within the realm of biochemical research, β-Alanine β-naphthylamide hydrobromide serves as a tool for examining the intricacies of enzyme catalysis and substrate specificity. By leveraging this compound, researchers can interrogate the kinetics of enzyme-substrate interactions, shedding light on the nuanced functions of enzymes and facilitating the design of enzyme inhibitors.

Diagnostic Applications: Diagnostic laboratories leverage β-Alanine β-naphthylamide hydrobromide to assess the presence and activity of specific enzymes, serving as biomarkers for various diseases. For instance, heightened aminopeptidase activity quantified using this substrate can signify particular pathological conditions. This diagnostic approach aids clinicians in both the diagnosis and monitoring of disease progression, contributing to enhanced patient care.

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