β-amyloid 1-11 acetate
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β-amyloid 1-11 acetate

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β-amyloid 1-11 acetate is a fragment of Amyloid-β peptide found in plaques associated with Alzheimer's disease.

Category
Peptide Inhibitors
Catalog number
BAT-016423
Molecular Formula
C58H80N16O24
Molecular Weight
1385.37
β-amyloid 1-11 acetate
IUPAC Name
acetic acid;(2S)-2-[[(2S)-2-[[2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-amino-3-carboxypropanoyl]amino]propanoyl]amino]-4-carboxybutanoyl]amino]-3-phenylpropanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-3-(1H-imidazol-5-yl)propanoyl]amino]-3-carboxypropanoyl]amino]-3-hydroxypropanoyl]amino]acetyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]pentanedioic acid
Synonyms
H-Asp-Ala-Glu-Phe-Arg-His-Asp-Ser-Gly-Tyr-Glu-OH.CH3CO2H; L-alpha-aspartyl-L-alanyl-L-alpha-glutamyl-L-phenylalanyl-L-arginyl-L-histidyl-L-alpha-aspartyl-L-seryl-glycyl-L-tyrosyl-L-glutamic acid acetic acid; b-amyloid 1-11 acetate
Related CAS
190436-05-6 (free base)
Purity
≥95%
Sequence
DAEFRHDSGYE.CH3CO2H
Storage
Store at -20°C
Solubility
Soluble in DMSO
InChI
InChI=1S/C56H76N16O22.C2H4O2/c1-27(64-47(85)32(57)21-44(80)81)46(84)66-34(13-15-42(76)77)50(88)69-37(18-28-6-3-2-4-7-28)52(90)67-33(8-5-17-61-56(58)59)49(87)70-38(20-30-23-60-26-63-30)53(91)71-39(22-45(82)83)54(92)72-40(25-73)48(86)62-24-41(75)65-36(19-29-9-11-31(74)12-10-29)51(89)68-35(55(93)94)14-16-43(78)79;1-2(3)4/h2-4,6-7,9-12,23,26-27,32-40,73-74H,5,8,13-22,24-25,57H2,1H3,(H,60,63)(H,62,86)(H,64,85)(H,65,75)(H,66,84)(H,67,90)(H,68,89)(H,69,88)(H,70,87)(H,71,91)(H,72,92)(H,76,77)(H,78,79)(H,80,81)(H,82,83)(H,93,94)(H4,58,59,61);1H3,(H,3,4)/t27-,32-,33-,34-,35-,36-,37-,38-,39-,40-;/m0./s1
InChI Key
MQJFZAUITKKLDZ-HFNVZVNISA-N
Canonical SMILES
CC(C(=O)NC(CCC(=O)O)C(=O)NC(CC1=CC=CC=C1)C(=O)NC(CCCN=C(N)N)C(=O)NC(CC2=CN=CN2)C(=O)NC(CC(=O)O)C(=O)NC(CO)C(=O)NCC(=O)NC(CC3=CC=C(C=C3)O)C(=O)NC(CCC(=O)O)C(=O)O)NC(=O)C(CC(=O)O)N.CC(=O)O
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