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Amyloid β-Protein (1-6) amide

* Please kindly note that our products are not to be used for therapeutic purposes and cannot be sold to patients.

Experiments using sub-peptides of Aβ42 show that the epitope identified by antibody A8 is located in the 1-6 region of Aβ.

Category

Functional Peptides

Catalog number

BAT-014843

CAS number

903883-21-6

Molecular Formula

C33H48N12O10

Molecular Weight

772.81

Specification

IUPAC Name

(4S)-4-[[(2S)-2-[[(2S)-2-amino-3-carboxypropanoyl]amino]propanoyl]amino]-5-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-5-oxopentanoic acid

Synonyms

L-Histidinamide, L-α-aspartyl-L-alanyl-L-α-glutamyl-L-phenylalanyl-L-arginyl-; H-Asp-Ala-Glu-Phe-Arg-His-NH2; H-DAEFRH-NH2; L-alpha-aspartyl-L-alanyl-L-alpha-glutamyl-L-phenylalanyl-L-arginyl-L-histidinamide

Appearance

White Powder

Purity

≥95%

Sequence

Asp-Ala-Glu-Phe-Arg-His-NH2

Storage

Store at -20°C

Solubility

Soluble in Water

InChI

InChI=1S/C33H48N12O10/c1-17(41-29(52)20(34)14-26(48)49)28(51)42-22(9-10-25(46)47)31(54)45-24(12-18-6-3-2-4-7-18)32(55)43-21(8-5-11-39-33(36)37)30(53)44-23(27(35)50)13-19-15-38-16-40-19/h2-4,6-7,15-17,20-24H,5,8-14,34H2,1H3,(H2,35,50)(H,38,40)(H,41,52)(H,42,51)(H,43,55)(H,44,53)(H,45,54)(H,46,47)(H,48,49)(H4,36,37,39)/t17-,20-,21-,22-,23-,24-/m0/s1

InChI Key

KZVTUPAXZZDFJR-YYOLRRQBSA-N

Canonical SMILES

CC(C(=O)NC(CCC(=O)O)C(=O)NC(CC1=CC=CC=C1)C(=O)NC(CCCN=C(N)N)C(=O)NC(CC2=CN=CN2)C(=O)N)NC(=O)C(CC(=O)O)N