[Asn1,Val5]-Angiotensin II acetate
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[Asn1,Val5]-Angiotensin II acetate

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[Asn1,Val5]-Angiotensin II acetate, an octapeptide amide of bovine angiotensin II, is used to increase blood pressure through vasoconstriction. It is a potent vasoconstrictor and a cardiac activator.

Category
Peptide Inhibitors
Catalog number
BAT-016402
CAS number
1233495-09-4
Molecular Formula
C51H74N14O13
Molecular Weight
1091.24
[Asn1,Val5]-Angiotensin II acetate
IUPAC Name
acetic acid;(2S)-2-[[(2S)-1-[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-5-(diaminomethylideneamino)-2-[[(2S)-2,4-diamino-4-oxobutanoyl]amino]pentanoyl]amino]-3-methylbutanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-3-methylbutanoyl]amino]-3-(1H-imidazol-5-yl)propanoyl]pyrrolidine-2-carbonyl]amino]-3-phenylpropanoic acid
Synonyms
H-Asn-Arg-Val-Tyr-Val-His-Pro-Phe-OH.CH3CO2H; L-asparagyl-L-arginyl-L-valyl-L-tyrosyl-L-valyl-L-histidyl-L-prolyl-L-phenylalanine acetic acid; Angiotensin II, 1-L-asparagine-5-L-valine-, acetate (1:1); 1-L-Asn-5-L-Val-angiotensin II acetate; Angiotensin II-5-valine-amide acetate; Hypertensin acetate; Hypertensinamide acetate; 1-L-Asparagine-5-L-valine angiotensin II acetate; Angiotensin amide acetate
Related CAS
53-73-6 (free base)
Purity
≥95%
Sequence
NRVYVHPF.CH3CO2H
Storage
Store at -20°C
Solubility
Soluble in DMSO
InChI
InChI=1S/C49H70N14O11.C2H4O2/c1-26(2)39(61-42(67)33(12-8-18-55-49(52)53)57-41(66)32(50)23-38(51)65)45(70)58-34(20-29-14-16-31(64)17-15-29)43(68)62-40(27(3)4)46(71)59-35(22-30-24-54-25-56-30)47(72)63-19-9-13-37(63)44(69)60-36(48(73)74)21-28-10-6-5-7-11-28;1-2(3)4/h5-7,10-11,14-17,24-27,32-37,39-40,64H,8-9,12-13,18-23,50H2,1-4H3,(H2,51,65)(H,54,56)(H,57,66)(H,58,70)(H,59,71)(H,60,69)(H,61,67)(H,62,68)(H,73,74)(H4,52,53,55);1H3,(H,3,4)/t32-,33-,34-,35-,36-,37-,39-,40-;/m0./s1
InChI Key
OJRHTSBKRRHZHU-IAQGTVMASA-N
Canonical SMILES
CC(C)C(C(=O)NC(CC1=CC=C(C=C1)O)C(=O)NC(C(C)C)C(=O)NC(CC2=CN=CN2)C(=O)N3CCCC3C(=O)NC(CC4=CC=CC=C4)C(=O)O)NC(=O)C(CCCN=C(N)N)NC(=O)C(CC(=O)N)N.CC(=O)O
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