(Asn370) tyrosinase (368-376)
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(Asn370) tyrosinase (368-376)

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(Asn370) tyrosinase (368-376) is a melanoma epitope of tyrosine founded in 40% of Caucasian. This skin cancer tumor antigenic peptide found in tyrosinase fragment presented in HLA-A2 class I molecule to CTLs.

Category
Others
Catalog number
BAT-009845
Molecular Formula
C42H67N11O15S2
Molecular Weight
1030.17
IUPAC Name
2-[[5-amino-2-[[2-[[2-[[2-[[2-[[4-amino-2-[[2-[[2-amino-3-(4-hydroxyphenyl)propanoyl]amino]-4-methylsulfanylbutanoyl]amino]-4-oxobutanoyl]amino]acetyl]amino]-3-hydroxybutanoyl]amino]-4-methylsulfanylbutanoyl]amino]-3-hydroxypropanoyl]amino]-5-oxopentanoyl]amino]-3-methylbutanoic acid
Synonyms
H-DL-Tyr-DL-Met-DL-Asn-Gly-DL-xiThr-DL-Met-DL-Ser-DL-Gln-DL-Val-OH
Purity
>95%
Sequence
YMNGTMSQV
Storage
Common storage 2-8°C, long time storage -20°C.
InChI
InChI=1S/C42H67N11O15S2/c1-20(2)33(42(67)68)53-39(64)25(10-11-30(44)57)48-40(65)29(19-54)51-38(63)27(13-15-70-5)49-41(66)34(21(3)55)52-32(59)18-46-36(61)28(17-31(45)58)50-37(62)26(12-14-69-4)47-35(60)24(43)16-22-6-8-23(56)9-7-22/h6-9,20-21,24-29,33-34,54-56H,10-19,43H2,1-5H3,(H2,44,57)(H2,45,58)(H,46,61)(H,47,60)(H,48,65)(H,49,66)(H,50,62)(H,51,63)(H,52,59)(H,53,64)(H,67,68)
InChI Key
XLNUFYWWDPBHOT-UHFFFAOYSA-N
Canonical SMILES
CC(C)C(C(=O)O)NC(=O)C(CCC(=O)N)NC(=O)C(CO)NC(=O)C(CCSC)NC(=O)C(C(C)O)NC(=O)CNC(=O)C(CC(=O)N)NC(=O)C(CCSC)NC(=O)C(CC1=CC=C(C=C1)O)N
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