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[Asp371]-Tyrosinase (369-377), human

* Please kindly note that our products are not to be used for therapeutic purposes and cannot be sold to patients.

It is derived from tyrosinase, a peptide fragment that controls melanin production and has been used to develop tumor-targeted vaccines with mixed efficacy.

Category

Peptide Inhibitors

Catalog number

BAT-010407

CAS number

168650-46-2

Molecular Formula

C42H66N10O16S2

Molecular Weight

1031.16

Specification

IUPAC Name

(2S)-2-[[(2S)-5-amino-2-[[(2S)-2-[[(2S)-2-[[(2S,3R)-2-[[2-[[(2S)-2-[[(2S)-2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]-4-methylsulfanylbutanoyl]amino]-3-carboxypropanoyl]amino]acetyl]amino]-3-hydroxybutanoyl]amino]-4-methylsulfanylbutanoyl]amino]-3-hydroxypropanoyl]amino]-5-oxopentanoyl]amino]-3-methylbutanoic acid

Synonyms

Tyrosinase Fragment 369-377 human; CMM8; OCA1A; OCAIA; SHEP3; TYR; Tyr-Met-Asp-Gly-Thr-Met-Ser-Gln-Val; L-tyrosyl-L-methionyl-L-alpha-aspartyl-glycyl-L-threonyl-L-methionyl-L-seryl-L-glutaminyl-L-valine

Appearance

White Lyophilized Powder

Purity

≥95%

Density

1.4±0.1 g/cm3

Boiling Point

1578.2±65.0°C at 760 mmHg

Sequence

YMDGTMSQV

Storage

Store in a cool and dry place and at 2-8°C for short term (days to weeks) or store at -20°C for long term (months to years)

Solubility

Soluble in Deionized Water

InChI

InChI=1S/C42H66N10O16S2/c1-20(2)33(42(67)68)52-39(64)25(10-11-30(44)56)47-40(65)29(19-53)50-38(63)27(13-15-70-5)48-41(66)34(21(3)54)51-31(57)18-45-36(61)28(17-32(58)59)49-37(62)26(12-14-69-4)46-35(60)24(43)16-22-6-8-23(55)9-7-22/h6-9,20-21,24-29,33-34,53-55H,10-19,43H2,1-5H3,(H2,44,56)(H,45,61)(H,46,60)(H,47,65)(H,48,66)(H,49,62)(H,50,63)(H,51,57)(H,52,64)(H,58,59)(H,67,68)/t21-,24+,25+,26+,27+,28+,29+,33+,34+/m1/s1

InChI Key

MFDQNJLLKIATDB-ZSGRDTBASA-N

Canonical SMILES

CC(C)C(C(=O)O)NC(=O)C(CCC(=O)N)NC(=O)C(CO)NC(=O)C(CCSC)NC(=O)C(C(C)O)NC(=O)CNC(=O)C(CC(=O)O)NC(=O)C(CCSC)NC(=O)C(CC1=CC=C(C=C1)O)N