Bax inhibitor peptide V5 acetate
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Bax inhibitor peptide V5 acetate

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Bax inhibitor peptide V5 acetate, a Bax-mediated apoptosis inhibitor, is a pro-apoptotic member of Bcl-2 family proteins and plays an important role in mitochondria-dependent apoptosis. It is used in cancer treatment.

Category
Peptide Inhibitors
Catalog number
BAT-016399
CAS number
2760881-58-9
Molecular Formula
C29H54N6O8S
Molecular Weight
646.85
Bax inhibitor peptide V5 acetate
IUPAC Name
acetic acid;(2S)-6-amino-2-[[(2S)-2-[[(2S)-2-[[(2S)-1-[(2S)-2-amino-3-methylbutanoyl]pyrrolidine-2-carbonyl]amino]-4-methylsulfanylbutanoyl]amino]-4-methylpentanoyl]amino]hexanoic acid
Synonyms
BIP-V5 acetate; H-Val-Pro-Met-Leu-Lys-OH.CH3CO2H; VPMLK acetate; L-valyl-L-prolyl-L-methionyl-L-leucyl-L-lysine acetic acid
Related CAS
579492-81-2 (free base)
Purity
≥95%
Sequence
Val-Pro-Met-Leu-Lys.CH3CO2H
Storage
Store at -20°C
Solubility
Soluble in DMSO, Water
InChI
InChI=1S/C27H50N6O6S.C2H4O2/c1-16(2)15-20(24(35)31-19(27(38)39)9-6-7-12-28)32-23(34)18(11-14-40-5)30-25(36)21-10-8-13-33(21)26(37)22(29)17(3)4;1-2(3)4/h16-22H,6-15,28-29H2,1-5H3,(H,30,36)(H,31,35)(H,32,34)(H,38,39);1H3,(H,3,4)/t18-,19-,20-,21-,22-;/m0./s1
InChI Key
OIZSUYGPMNZUGB-QXJGFYJDSA-N
Canonical SMILES
CC(C)CC(C(=O)NC(CCCCN)C(=O)O)NC(=O)C(CCSC)NC(=O)C1CCCN1C(=O)C(C(C)C)N.CC(=O)O
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