Benzoyl-L-alanine β-naphthylamide
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Benzoyl-L-alanine β-naphthylamide

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Category
L-Amino Acids
Catalog number
BAT-003911
CAS number
201988-47-8
Molecular Formula
C20H18N2O2
Molecular Weight
318.20
Benzoyl-L-alanine β-naphthylamide
IUPAC Name
N-[(2S)-1-(naphthalen-2-ylamino)-1-oxopropan-2-yl]benzamide
Synonyms
Bz-L-Ala-Βna; (S)-N-(1-(Naphthalen-2-ylamino)-1-oxopropan-2-yl)benzamide
Appearance
White powder
Storage
Store at 2-8 °C
InChI
InChI=1S/C20H18N2O2/c1-14(21-20(24)16-8-3-2-4-9-16)19(23)22-18-12-11-15-7-5-6-10-17(15)13-18/h2-14H,1H3,(H,21,24)(H,22,23)/t14-/m0/s1
InChI Key
RSVUNQQWZZPHKB-AWEZNQCLSA-N
Canonical SMILES
CC(C(=O)NC1=CC2=CC=CC=C2C=C1)NC(=O)C3=CC=CC=C3

Benzoyl-L-alanine β-naphthylamide, a biochemical compound widely utilized in scientific research and diagnostics, presents diverse applications. Here are four key uses characterized by high perplexity and burstiness:

Protease Activity Assays: Serving as a substrate in protease activity assays, Benzoyl-L-alanine β-naphthylamide is a cornerstone in enzymology research. When acted upon by proteases, this compound yields a measurable fluorescent or colorimetric product, enabling quantitative analysis. This method is indispensable for profiling protease enzymes and screening potential inhibitors, shedding light on intricate enzyme-substrate interactions.

Biochemical Research: As a fundamental tool in enzyme kinetics studies, Benzoyl-L-alanine β-naphthylamide facilitates in-depth investigations into catalytic mechanisms and specificities of proteases. By utilizing this compound, researchers can dissect the catalytic efficiency of diverse proteases and decipher their substrate preferences, providing valuable insights for designing tailored enzyme inhibitors and therapeutic strategies.

Diagnostic Applications: In the realm of clinical diagnostics, Benzoyl-L-alanine β-naphthylamide plays a vital role in detecting disease-associated protease activities. Integration of this compound into diagnostic assays enables clinicians to pinpoint proteolytic activity markers linked to conditions such as cancer or bacterial infections. This enhances diagnostic precision, enabling early disease detection and monitoring through the lens of protease biology.

Pharmaceutical Development: Within the pharmaceutical sector, Benzoyl-L-alanine β-naphthylamide fuels high-throughput screening initiatives for compound libraries. By assessing the impact of potential drug candidates on protease activity inhibition, researchers can pinpoint promising leads for drug development targeting protease-related disorders. This accelerates the discovery of novel therapeutic agents, driving innovation in pharmaceutical interventions.

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