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Beta-Sheet Breaker Peptide iAβ5 acetate

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Beta-Sheet Breaker Peptide iAβ5 acetate inhibits amyloid formation in rat brain models.

Category

Peptide Inhibitors

Catalog number

BAT-016202

CAS number

2763585-09-5

Molecular Formula

C35H47N5O10

Molecular Weight

697.78

Specification

IUPAC Name

acetic acid;(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-1-[(2S)-2-amino-4-methylpentanoyl]pyrrolidine-2-carbonyl]amino]-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]butanedioic acid

Synonyms

Beta-Sheet Breaker Peptide iA(c)micro5 Acetate; H-Leu-Pro-Phe-Phe-Asp-OH.CH3CO2H; L-leucyl-L-prolyl-L-phenylalanyl-L-phenylalanyl-L-aspartic acid acetic acid; LPFFD.CH3CO2H; Acetic acid, compd. with (L-leucyl-yl-L-phenylalanyl-yl-L-prolyl-yl-L-phenylalanyl-yl)-L-Aspartate (1:1)

Related CAS

182912-74-9 (free base)

Purity

≥95%

Sequence

Leu-Pro-Phe-Phe-Asp.CH3CO2H

Storage

Store at -20°C

Solubility

Soluble in DMSO

InChI

InChI=1S/C33H43N5O8.C2H4O2/c1-20(2)16-23(34)32(44)38-15-9-14-27(38)31(43)36-25(18-22-12-7-4-8-13-22)29(41)35-24(17-21-10-5-3-6-11-21)30(42)37-26(33(45)46)19-28(39)40;1-2(3)4/h3-8,10-13,20,23-27H,9,14-19,34H2,1-2H3,(H,35,41)(H,36,43)(H,37,42)(H,39,40)(H,45,46);1H3,(H,3,4)/t23-,24-,25-,26-,27-;/m0./s1

InChI Key

SDNHANHEHYOWMZ-HYRZFBCKSA-N

Canonical SMILES

CC(C)CC(C(=O)N1CCCC1C(=O)NC(CC2=CC=CC=C2)C(=O)NC(CC3=CC=CC=C3)C(=O)NC(CC(=O)O)C(=O)O)N.CC(=O)O