Boc-3-(2'-pyridyl)-L-alanine
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Boc-3-(2'-pyridyl)-L-alanine

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Category
BOC-Amino Acids
Catalog number
BAT-007961
CAS number
71239-85-5
Molecular Formula
C13H18N2O4
Molecular Weight
266.29
Boc-3-(2'-pyridyl)-L-alanine
IUPAC Name
(2S)-2-[(2-methylpropan-2-yl)oxycarbonylamino]-3-pyridin-2-ylpropanoic acid
Synonyms
Boc-L-Ala(2'-pyridyl)-OH; (S)-2-tert-Butoxycarbonylamino-3-pyridin-2-yl-propionic acid; Boc-L-2-Pyridylalanine; BOC-2-PAL-OH; Boc-L-3-(2-pyridyl)-alanine; Boc-Ala(2-pyridyl)-OH; Boc-3-(2-pyridyl)-Ala-OH; BOC-2'-PYRIDYL-L-ALA; N-Boc-3-(2-pyridyl)-L-alanine; N-(tert-butoxycarbonyl)-3-pyridin-2-yl-L-alanine; (2S)-2-[(tert-butoxy)carbonylamino]-3-(2-pyridyl)propanoic acid
Appearance
White powder
Purity
≥ 99% (HPLC)
Density
1.200 g/cm3
Melting Point
140-143 °C
Boiling Point
436.9 °C at 760 mmHg
Storage
Store at 2-8 °C
InChI
InChI=1S/C13H18N2O4/c1-13(2,3)19-12(18)15-10(11(16)17)8-9-6-4-5-7-14-9/h4-7,10H,8H2,1-3H3,(H,15,18)(H,16,17)/t10-/m0/s1
InChI Key
KMODKKCXWFNEIK-JTQLQIEISA-N
Canonical SMILES
CC(C)(C)OC(=O)NC(CC1=CC=CC=N1)C(=O)O

Boc-3-(2'-pyridyl)-L-alanine, a versatile chemical compound used in bioscience research and development, boasts a wide array of applications. Here are the key applications presented with high perplexity and burstiness:

Peptide Synthesis: A cornerstone in peptide synthesis, Boc-3-(2'-pyridyl)-L-alanine plays a fundamental role as a building block, incorporating pyridyl groups into peptide chains. This unique feature offers advantages in stabilizing secondary structures and facilitating specific biochemical interactions. Researchers leverage this compound to craft tailored peptides for diverse research endeavors and therapeutic interventions.

Protein Engineering: In the realm of protein engineering, Boc-3-(2'-pyridyl)-L-alanine emerges as a pivotal player, capable of being introduced into proteins through site-directed mutagenesis. The presence of the pyridyl group enables modulation of protein function and creation of novel binding sites within engineered proteins. This application proves invaluable for investigating protein-ligand interactions and forging innovative protein-based therapeutics.

Chemical Probes: With its potential as a chemical probe, Boc-3-(2'-pyridyl)-L-alanine serves as a valuable tool for probing biological processes. The pyridyl group lends versatility in designing ligands that selectively interact with enzymes or receptors, enabling researchers to dissect intricate biochemical pathways and pinpoint potential drug targets. These probes serve as critical instruments in unraveling the complexities of biological systems.

Medicinal Chemistry: In the realm of medicinal chemistry, Boc-3-(2'-pyridyl)-L-alanine emerges as a game-changer, facilitating the development of novel drug candidates. Its unique structure enhances the pharmacokinetic and pharmacodynamic properties of small molecule drugs, paving the way for the discovery of more potent and specific therapeutic agents. Integrating this compound into drug design holds the promise of unlocking new avenues in therapeutic innovation and drug development.

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