Boc-3-(3'-pyridyl)-D-alanine
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Boc-3-(3'-pyridyl)-D-alanine

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Boc-3-(3'-pyridyl)-D-alanine is an alanine derivative, used in various chemical synthesis and peptide chemistry.

Category
BOC-Amino Acids
Catalog number
BAT-007964
CAS number
98266-33-2
Molecular Formula
C13H18N2O4
Molecular Weight
266.29
Boc-3-(3'-pyridyl)-D-alanine
IUPAC Name
(2R)-2-[(2-methylpropan-2-yl)oxycarbonylamino]-3-pyridin-3-ylpropanoic acid
Synonyms
Boc-D-Ala(3'-pyridyl)-OH; Boc-(R)-2-amino-3-(3'-pyridyl)propanoic acid; Boc-D-3-Pyridylalanine; BOC-D-3-PAL-OH; Boc-3-(3-pyridyl)-D-alanine; (R)-2-((tert-Butoxycarbonyl)amino)-3-(pyridin-3-yl)propanoic acid; BOC-D-3-(3-PYRIDYL)-ALANINE; Boc-D-Pal; N-tert-Butoxycarbonyl-3-pyridyl-D-alanine; Boc D Pal
Appearance
White powder
Purity
≥ 98% (HPLC)
Density
1.200 g/cm3
Melting Point
134-148 °C
Boiling Point
452.9 °C at 760 mmHg
Storage
Store at 2-8 °C
InChI
InChI=1S/C13H18N2O4/c1-13(2,3)19-12(18)15-10(11(16)17)7-9-5-4-6-14-8-9/h4-6,8,10H,7H2,1-3H3,(H,15,18)(H,16,17)/t10-/m1/s1
InChI Key
JLBCSWWZSSVXRQ-SNVBAGLBSA-N
Canonical SMILES
CC(C)(C)OC(=O)NC(CC1=CN=CC=C1)C(=O)O

Boc-3-(3'-pyridyl)-D-alanine a vital compound in organic and medicinal chemistry boasts a diverse array of applications Discover the versatility of Boc-3-(3'-pyridyl)-D-alanine through these intricately presented key applications:

Drug Design and Development: A cornerstone in peptide-based drug synthesis, Boc-3-(3'-pyridyl)-D-alanine plays a pivotal role in enhancing the stability and bioavailability of peptide sequences. Its integration elevates the potential for crafting innovative therapeutics targeting a spectrum of diseases from cancer to infectious ailments showcasing its indispensable value in cutting-edge pharmaceutical advancements.

Peptide Synthesis: Within the realm of peptide synthesis, Boc-3-(3'-pyridyl)-D-alanine emerges as a safeguard against undesired side reactions enabling the controlled assembly of intricate peptide chains Post-synthesis the removal of the Boc group under mild conditions yields the anticipated peptide underscoring the compound's crucial role in facilitating the precise construction of peptides with complex structures.

Enzyme Inhibition Studies: At the forefront of enzyme research scientists harness, Boc-3-(3'-pyridyl)-D-alanine to engineer and scrutinize enzyme inhibitors By incorporating this compound into inhibitor molecules researchers unravel the intricate dance between the inhibitor and its designated enzyme target offering profound insights into enzyme functionality. This exploration serves to catalyze the development of potent enzyme inhibitors for therapeutic applications driving innovation in the realm of enzyme-based treatments.

Structural Biology: In the realm of structural biology, Boc-3-(3'-pyridyl)-D-alanine emerges as a crucial tool for introducing conformational constraints into peptide structures fostering the stabilization of specific secondary structures like alpha helices and beta sheets. This application is pivotal for delving into protein folding intricacies and for tailoring peptides with desired structural and functional attributes underscoring the compound's pivotal role in advancing our understanding of biomolecular architecture.

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