Boc-3-(4-pyridyl)-D-alanine
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Boc-3-(4-pyridyl)-D-alanine

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Category
BOC-Amino Acids
Catalog number
BAT-007966
CAS number
37535-58-3
Molecular Formula
C13H18N2O4
Molecular Weight
266.29
Boc-3-(4-pyridyl)-D-alanine
IUPAC Name
(2R)-2-[(2-methylpropan-2-yl)oxycarbonylamino]-3-pyridin-4-ylpropanoic acid
Synonyms
Boc-D-Ala(4'-pyridyl)-OH; (R)-N-Boc-(4'-pyridyl)alanine; BOC-D-4-PYRIDYLALANINE; Boc-D-4-Pal-OH; (R)-2-((tert-Butoxycarbonyl)amino)-3-(pyridin-4-yl)propanoic acid; (2R)-2-[(tert-butoxy)carbonylamino]-3-(4-pyridyl)propanoic acid; BOC-4'-PYRIDYL-D-ALA; BOC-D-ALA(4-PYRI)-OH; Boc-3-(4-pyridyl)-D-Ala-OH
Appearance
White powder
Purity
≥ 99% (HPLC)
Density
1.200 g/cm3
Melting Point
226-232 °C
Boiling Point
454.3 °C at 760 mmHg
Storage
Store at 2-8 °C
InChI
InChI=1S/C13H18N2O4/c1-13(2,3)19-12(18)15-10(11(16)17)8-9-4-6-14-7-5-9/h4-7,10H,8H2,1-3H3,(H,15,18)(H,16,17)/t10-/m1/s1
InChI Key
FNYWDMKESUACOU-SNVBAGLBSA-N
Canonical SMILES
CC(C)(C)OC(=O)NC(CC1=CC=NC=C1)C(=O)O

Boc-3-(4-pyridyl)-D-alanine, a chemical compound widely applied in bioscience research and drug development, serves as a versatile tool in scientific endeavors. Here are the key applications creatively presented with a high degree of perplexity and burstiness:

Peptide Synthesis: Embarking on the journey of peptide synthesis, researchers frequently employ Boc-3-(4-pyridyl)-D-alanine as a foundational component. Its integration facilitates the creation of peptides endowed with specific properties crucial for probing protein-protein interactions. The shielding Boc group accompanying this compound simplifies the manipulation of peptide chains during the synthetic process paving the way for intricate peptide construction.

Drug Development: Pioneering the realm of pharmaceutical innovation, Boc-3-(4-pyridyl)-D-alanine assumes a pivotal role in crafting novel therapeutic agents. By delicately altering its molecular structure scientists can engineer compounds boasting heightened efficacy and diminished side effects. This involvement in lead compound evolution stands as a cornerstone in the quest for more potent medications shaping the landscape of pharmacological advancements.

Structural Biology: Unveiling the mysteries of molecular architecture, Boc-3-(4-pyridyl)-D-alanine emerges as a valuable asset in stabilizing proteins and peptides for structural investigations. Its inclusion in peptide sequences aids in the formation of durable and crystallizable protein complexes facilitating the exploration of the intricate three-dimensional structures of biological macromolecules. This contribution propels the boundaries of structural elucidation in biological studies.

Enzyme Inhibition Studies: Delving into the intricate realm of enzyme inhibition mechanisms, researchers leverage Boc-3-(4-pyridyl)-D-alanine to unravel the mysteries of enzyme-substrate interactions. By incorporating this compound into substrate analogs, scientists dissect the intricate dance between enzymes and their substrates identifying prospective inhibitors in the process. These profound insights serve as pillars for the development of enzyme-targeted therapeutics illuminating new avenues in drug discovery.

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