Boc-Cys(Trt)-OH DCHA
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Boc-Cys(Trt)-OH DCHA

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Category
BOC-Amino Acids
Catalog number
BAT-000788
CAS number
26988-59-0
Molecular Formula
C27H29NO4S·C12H23N
Molecular Weight
644.6
IUPAC Name
N-cyclohexylcyclohexanamine;(2R)-2-[(2-methylpropan-2-yl)oxycarbonylamino]-3-tritylsulfanylpropanoic acid
Synonyms
Dicyclohexylamine (R)-2-((tert-butoxycarbonyl)amino)-3-(tritylthio)propanoate
Storage
Store at 2-8 °C
InChI
InChI=1S/C27H29NO4S.C12H23N/c1-26(2,3)32-25(31)28-23(24(29)30)19-33-27(20-13-7-4-8-14-20,21-15-9-5-10-16-21)22-17-11-6-12-18-22;1-3-7-11(8-4-1)13-12-9-5-2-6-10-12/h4-18,23H,19H2,1-3H3,(H,28,31)(H,29,30);11-13H,1-10H2/t23-;/m0./s1
InChI Key
XIKHCNDMEGATRK-BQAIUKQQSA-N
Canonical SMILES
CC(C)(C)OC(=O)NC(CSC(C1=CC=CC=C1)(C2=CC=CC=C2)C3=CC=CC=C3)C(=O)O.C1CCC(CC1)NC2CCCCC2

Boc-Cys(Trt)-OH DCHA, a chemical compound integral to peptide synthesis, finds diverse applications in various fields. Here are four key applications explored with a high degree of perplexity and burstiness:

Peptide Synthesis: Central to solid-phase peptide synthesis is the role of Boc-Cys(Trt)-OH DCHA as a protective group for cysteine residues. By shielding cysteine, it prevents inadvertent side reactions during the peptide elongation process. Upon completion of synthesis, the protective group is selectively removed, unveiling the final peptide product, crucial for both research endeavors and therapeutic developments.

Protein Engineering: In the realm of protein manipulation, Boc-Cys(Trt)-OH DCHA emerges as a catalyst for introducing cysteine residues at predetermined locations within proteins. These cysteine residues can either form disulfide bonds or act as anchoring points for diverse functional groups. This capability to alter protein structures is fundamental to crafting novel proteins exhibiting enhanced or modified functionalities.

Drug Development: Within the realm of drug discovery, Boc-Cys(Trt)-OH DCHA plays a vital role in synthesizing peptide-based drugs. Its usage facilitates the creation of cysteine-rich peptides, known for their high binding affinities and specificities toward target molecules. This attribute positions Boc-Cys(Trt)-OH DCHA as a crucial reagent in developing peptides with therapeutic potential across a spectrum of diseases.

Bioconjugation: Diving into bioconjugation practices, Boc-Cys(Trt)-OH DCHA shines as a key component in forming peptide conjugates by linking peptides with other entities like drugs, dyes, or nanoparticles. The cysteine residue serves as a versatile anchor for such modifications, allowing for customizable functionalization. Widely utilized in creating targeted drug delivery systems and advanced diagnostic tools, this technique showcases the versatility and adaptability of Boc-Cys(Trt)-OH DCHA in driving innovative biomedical solutions.

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