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Boc-D-Asp(OMe)-OH, a derivative of protected amino acid, is a cornerstone in peptide synthesis and pharmaceutical research. Explore its diverse applications with a touch of high perplexity and burstiness:
Peptide Synthesis: Embracing Boc-D-Asp(OMe)-OH in solid-phase peptide synthesis (SPPS) unveils its role as a fundamental building block. The Boc (tert-butyloxycarbonyl) protective group facilitates the gradual construction of peptides by shielding the amino group during coupling reactions. Upon completion of the peptide assembly, the protective groups are meticulously eliminated to unveil the ultimate product.
Drug Development: Witness the transformative potential of Boc-D-Asp(OMe)-OH in sculpting peptide-based drug candidates. Its integration into peptide chains elevates stability, bioavailability, and therapeutic activity. Researchers harness this compound to forge novel medications targeting a spectrum of ailments, from cancer and diabetes to infectious diseases, resonating with a profound impact on pharmaceutical advancement.
Biochemical Research: Unravel the intricate realms of protein-protein interactions and enzyme-substrate dynamics through the lens of Boc-D-Asp(OMe)-OH in biochemical studies. By infusing this amino acid into peptides, scientists delve into the intricacies of how structural modifications influence biological function. This exploration forms the bedrock of disease mechanism investigations, paving the way for tailored enzyme inhibitors and substrates.
Proteomics: Venture into the realm of proteomic analysis with Boc-D-Asp(OMe)-OH as a strategic ally. Craft specialized reagents for proteomics by incorporating modified peptides containing this derivative. These peptides emerge as indispensable standards or probes in mass spectrometry-based proteomics, essential for unraveling the identities and quantities of proteins in intricate biological samples.
