Boc-D-Cys(MBzl)-ol
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Boc-D-Cys(MBzl)-ol

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Category
Amino Alcohol
Catalog number
BAT-000605
CAS number
129397-85-9
Molecular Formula
C16H25NO3S
Molecular Weight
311.4
Boc-D-Cys(MBzl)-ol
IUPAC Name
tert-butyl N-[(2S)-1-hydroxy-3-[(4-methylphenyl)methylsulfanyl]propan-2-yl]carbamate
Synonyms
Boc-Cysteinol(pmebzl); Boc-D-Cysteinol(pmebzl); tert-butyl N-[(2S)-1-hydroxy-3-[(4-methylphenyl)methylsulfanyl]propan-2-yl]carbamate
Storage
Store at 2-8 °C
InChI
InChI=1S/C16H25NO3S/c1-12-5-7-13(8-6-12)10-21-11-14(9-18)17-15(19)20-16(2,3)4/h5-8,14,18H,9-11H2,1-4H3,(H,17,19)/t14-/m0/s1
InChI Key
OZZBJMHSOZAQBJ-AWEZNQCLSA-N
Canonical SMILES
CC1=CC=C(C=C1)CSCC(CO)NC(=O)OC(C)(C)C

Boc-D-Cys(MBzl)-ol, a versatile protective amino acid derivative, finds widespread applications in peptide synthesis and bioscience research. Here are four key applications:

Peptide Synthesis: Acting as a crucial building block in peptide chemical synthesis, Boc-D-Cys(MBzl)-ol offers exceptional stability and protective properties, making it the preferred choice for assembling intricate peptide sequences. Researchers leverage its precision to craft tailored peptides for drug development and biochemical explorations, employing a controlled approach to peptide construction.

Drug Development: Spearheading advancements in pharmaceutical research, Boc-D-Cys(MBzl)-ol serves as a cornerstone in synthesizing peptide-based drug candidates. The strategic inclusion of the Boc protecting group facilitates selective deprotection and peptide modification, streamlining the creation of drug molecules with precise biological activity and robust stability, thus paving the way for innovative therapeutic solutions.

Protein Engineering: At the forefront of protein innovation, Boc-D-Cys(MBzl)-ol features prominently in the engineering of proteins with novel functionalities or enhanced attributes. By integrating this derivative into protein sequences, scientists can introduce targeted modifications or fortify protein structures, a pivotal step in the design of therapeutic proteins and industrial enzymes, driving progress in biotechnological applications.

Bioconjugation: Fueling advancements in bioconjugation techniques, Boc-D-Cys(MBzl)-ol enables the linking of peptides or proteins to diverse entities, such as drugs, imaging agents, or nanoparticles, with precision and efficiency. Leveraging its functional group, this derivative facilitates specific and effective coupling reactions—a crucial process in developing cutting-edge targeted delivery systems and diagnostic tools.

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