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Application Area

Boc-D-Leucinol

* Please kindly note that our products are not to be used for therapeutic purposes and cannot be sold to patients.

Category

Amino Alcohol

Catalog number

BAT-002592

CAS number

106930-51-2

Molecular Formula

C11H23NO3

Molecular Weight

217.31

Specification
Reference Reading

IUPAC Name

tert-butyl N-[(2R)-1-hydroxy-4-methylpentan-2-yl]carbamate

Synonyms

Boc-D-Leu-ol; N-BOC-D-Leucinol; (R)-tert-Butyl (1-hydroxy-4-methylpentan-2-yl)carbamate

Appearance

Light yellowish liquid

Purity

≥ 97% (HPLC)

Density

0.984 g/mL

Boiling Point

213 °C

Storage

Store at 2-8 °C

InChI

InChI=1S/C11H23NO3/c1-8(2)6-9(7-13)12-10(14)15-11(3,4)5/h8-9,13H,6-7H2,1-5H3,(H,12,14)/t9-/m1/s1

InChI Key

LQTMEOSBXTVYRM-SECBINFHSA-N

Canonical SMILES

CC(C)CC(CO)NC(=O)OC(C)(C)C

1.Synthesis of the C-13 side chain precursors of the 9-dihydrotaxane analogue ABT-271.

Leanna MR1, DeMattei JA, Li W, Nichols PJ, Rasmussen M, Morton HE. Org Lett. 2000 Nov 16;2(23):3627-30.

N-Boc-L-Leucinol was converted to two C-13 side chain precursors of the 9-dihydrotaxane analogue ABT-271. The trans-oxazolidine acid 4 and the cis-Boc-lactam 2b were prepared in 44% and 40% overall yield, respectively, and with excellent (>98%) stereochemical purity.