Boc-D-trans-Hyp-OH
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Boc-D-trans-Hyp-OH

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Boc-D-trans-Hyp-OH is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). It is also an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs.

Category
Cyclic Amino Acids
Catalog number
BAT-001270
CAS number
147266-92-0
Molecular Formula
C10H17NO5
Molecular Weight
231.25
Boc-D-trans-Hyp-OH
IUPAC Name
(2R,4S)-4-hydroxy-1-[(2-methylpropan-2-yl)oxycarbonyl]pyrrolidine-2-carboxylic acid
Synonyms
(2R,4S)-1-(tert-butoxycarbonyl)-4-hydroxypyrrolidine-2-carboxylic acid; N-Boc-trans-4-hydroxy-d-proline
Purity
≥ 97%
Density
1.312±0.06 g/cm3
Melting Point
123°C
Boiling Point
390.9±42.0°C
InChI
InChI=1S/C10H17NO5/c1-10(2,3)16-9(15)11-5-6(12)4-7(11)8(13)14/h6-7,12H,4-5H2,1-3H3,(H,13,14)/t6-,7+/m0/s1
InChI Key
BENKAPCDIOILGV-NKWVEPMBSA-N
Canonical SMILES
CC(C)(C)OC(=O)N1CC(CC1C(=O)O)O
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