Boc-Glu-Obzl DCHA
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Boc-Glu-Obzl DCHA

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Category
BOC-Amino Acids
Catalog number
BAT-000824
CAS number
30924-91-5
Molecular Formula
C17H23NO6·C12H23N
Molecular Weight
518.4
IUPAC Name
N-cyclohexylcyclohexanamine;(4S)-4-[(2-methylpropan-2-yl)oxycarbonylamino]-5-oxo-5-phenylmethoxypentanoic acid
Synonyms
Dicyclohexylamine (4S)-4-[(2-methylpropan-2-yl)oxycarbonylamino]-5-oxo-5-phenylmethoxypentanoic acid
Storage
Store at 2-8 °C
InChI
InChI=1S/C17H23NO6.C12H23N/c1-17(2,3)24-16(22)18-13(9-10-14(19)20)15(21)23-11-12-7-5-4-6-8-12;1-3-7-11(8-4-1)13-12-9-5-2-6-10-12/h4-8,13H,9-11H2,1-3H3,(H,18,22)(H,19,20);11-13H,1-10H2/t13-;/m0./s1
InChI Key
XKYXIVNBTCGYSE-ZOWNYOTGSA-N
Canonical SMILES
CC(C)(C)OC(=O)NC(CCC(=O)O)C(=O)OCC1=CC=CC=C1.C1CCC(CC1)NC2CCCCC2

Boc-Glu-Obzl DCHA, a versatile chemical compound essential in peptide synthesis and various biochemical applications, boasts a myriad of uses in the scientific domain. Here are four key applications intricately:

Peptide Synthesis: Operating within the intricate realm of peptide synthesis, Boc-Glu-Obzl DCHA plays a pivotal role as a protecting group, particularly in solid-phase peptide synthesis. By selectively shielding the amino group of glutamic acid, this compound expedites the sequential addition of other amino acids, ensuring the meticulous assembly of peptide chains indispensable for unraveling protein functionalities and nurturing the advancement of peptide-based pharmaceuticals.

Biochemical Research: Embarking on a journey into biochemical research unveils Boc-Glu-Obzl DCHA as a critical instrument for crafting modified peptides that shed light on enzyme-substrate interactions. Scientists harness these analogs to decipher enzyme specificity and catalytic mechanisms, laying the groundwork for developing enzyme inhibitors and expanding our understanding of metabolic pathways.

Pharmaceutical Development: In the sphere of pharmaceutical development, this compound serves as a foundational unit in creating therapeutic peptides. By safeguarding specific functional groups during synthesis, Boc-Glu-Obzl DCHA ensures the stability and efficacy of the final peptide product. These peptides emerge as vital components of drug discovery endeavors targeting ailments like cancer, metabolic disorders, and infectious diseases.

Medicinal Chemistry: Nestled at the heart of medicinal chemistry, Boc-Glu-Obzl DCHA acts as a linchpin in the design and synthesis of novel peptidomimetics—compounds mirroring peptide structures. Leveraging enhanced stability and bioavailability, these peptidomimetics stand as potent therapeutic agents. Medicinal chemists rely on this compound to explore new pathways in drug development, striving to create novel drug candidates with heightened efficacy and minimized side effects.

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