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Boc-O-methyl-L-threonine

* Please kindly note that our products are not to be used for therapeutic purposes and cannot be sold to patients.

Category

BOC-Amino Acids

Catalog number

BAT-002871

CAS number

48068-25-3

Molecular Formula

C10H19NO5

Molecular Weight

233.26

Specification
Reference Reading

IUPAC Name

(2S,3R)-3-methoxy-2-[(2-methylpropan-2-yl)oxycarbonylamino]butanoic acid

Synonyms

Boc-L-Thr(Me)-OH; (2S,3R)-2-((tert-Butoxycarbonyl)amino)-3-methoxybutanoic acid

Appearance

White to off-white powder

Purity

98-102% (Assay)

Density

1.123±0.06 g/cm3(Predicted)

Boiling Point

362.1±37.0 °C(Predicted)

Storage

Store at 2-8°C

InChI

InChI=1S/C10H19NO5/c1-6(15-5)7(8(12)13)11-9(14)16-10(2,3)4/h6-7H,1-5H3,(H,11,14)(H,12,13)/t6-,7+/m1/s1

InChI Key

VWSUOKFUIPMDDX-RQJHMYQMSA-N

Canonical SMILES

CC(C(C(=O)O)NC(=O)OC(C)(C)C)OC

1.Human proinsulin, V: synthesis of a protected peptide fragment corresponding to the sequence 24-45 of the prohormone.

Föhles J, Danho W. Hoppe Seylers Z Physiol Chem. 1980;361(6):849-56.

The protected peptide fragment 24-45 of human proinsulin, Bpoc-Phe-Phe-Tyr(But)-Thr-(But)-Pro-Lys(Boc)-Thr(But)-Arg(H2SO4)-Arg-(H2SO4)-Gl u(OBut)-Ala-Glu(OBut)-Asp(OBut)-Leu-Gln-Val-Gly-Gin-Val-Glu(OBut)-Leu-Gly-Oh, was synthesized from the two intermediate fragments 24--33 and 34--45, and purified by countercurrent distribution in the carbon tetrachloride system (K = 2.5).