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Boc-Tyr(OtBu)-Glu(OtBu)-Gly-OH is a protected tripeptide used in peptide synthesis. The Boc (tert-Butoxycarbonyl) group protects the N-terminus of the tyrosine (Tyr) residue, preventing it from reacting during synthesis. The side chain carboxyl groups of both the glutamic acid (Glu) and tyrosine residues are protected by OtBu (tert-butyl) groups, which safeguard these functional groups until they are selectively deprotected. Gly (Glycine), the final amino acid in the sequence, has a free carboxyl group at the C-terminus, indicated by -OH, allowing for further peptide coupling or modifications. This compound is used to introduce tyrosine, glutamic acid, and glycine into peptides, with controlled reactivity through specific protective groups to ensure efficient and selective synthesis.
