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Brevinin-2DYb

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Brevinin-2DYb is an antimicrobial peptide found in Rana dybowskii (Dybovsky's frog, Korean brown frog). It has antibacterial activity against Gram-negative bacterium: Escherichia coli (MIC=30 µM) and Gram-positive bacterium: Staphylococcus aureus (MIC=30 µM).

Category
Functional Peptides
Catalog number
BAT-012951
Molecular Formula
C145H248N40O42S2
Molecular Weight
3287.94
IUPAC Name
(3S,6S,9S,12S,18S,21S,24S,30S,36S,39S,42S,45S,51S,54S,57S,60S)-60-(((S)-5-amino-1-(((S)-1-(((S)-6-amino-1-(((4R,13S,16S,19S,22R)-19-(4-aminobutyl)-4-carboxy-13-(hydroxymethyl)-16-isobutyl-6,9,12,15,18,21-hexaoxo-1,2-dithia-5,8,11,14,17,20-hexaazacyclotricosan-22-yl)amino)-1-oxohexan-2-yl)amino)-4-methyl-1-oxopentan-2-yl)amino)-1,5-dioxopentan-2-yl)carbamoyl)-39-(2-amino-2-oxoethyl)-3-((S)-2-((S)-2-(2-aminoacetamido)-4-methylpentanamido)-3-phenylpropanamido)-12,24,36-tris(4-aminobutyl)-51-(hydroxymethyl)-21,54,57-triisobutyl-6,9,18,42-tetraisopropyl-30,45-dimethyl-4,7,10,13,16,19,22,25,28,31,34,37,40,43,46,49,52,55,58-nonadecaoxo-5,8,11,14,17,20,23,26,29,32,35,38,41,44,47,50,53,56,59-nonadecaazatrihexacontanedioic acid
Synonyms
Gly-Leu-Phe-Asp-Val-Val-Lys-Gly-Val-Leu-Lys-Gly-Ala-Gly-Lys-Asn-Val-Ala-Gly-Ser-Leu-Leu-Glu-Gln-Leu-Lys-Cys-Lys-Leu-Ser-Gly-Gly-Cys (Disulfide bridge: Cys27-Cys33)
Appearance
Lyophilized Powder or Liquid
Purity
>96%
Sequence
GLFDVVKGVLKGAGKNVAGSLLEQLKCKLSGGC (Disulfide bridge: Cys27-Cys33)
Storage
Store at -20°C
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