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Brevinin-2E-OG1

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Brevinin-2E-OG1 is an antimicrobial peptide found in Rana grahami (Odorrana grahami, Yunnanfu frog). It has antimicrobial activity against Gram-negative bacteria: Escherichia coli, Bacillus pyocyaneus CMCCB 10104 (MIC=6.6 µg/ml), Gram-positive bacterium: Staphylococcus aureus and Yeast: Candida albicans (MIC=6.6 µg/ml).

Category
Functional Peptides
Catalog number
BAT-012963
Molecular Formula
C145H248N40O45S3
Molecular Weight
3367.99
IUPAC Name
(4R,7S,10S,13S,16S,19S,22R)-22-((2S,5S,8S,11S,14S,17S,20S,23S,29S,32S,35S,38S,41S,44S,47S,50S,53S,56S,59S,62S,65S,68S,71S,74S)-77-amino-11,44,56-tris(2-amino-2-oxoethyl)-35,59-bis(4-aminobutyl)-62-benzyl-68-(carboxymethyl)-65-((R)-1-hydroxyethyl)-2,20,32-tris(hydroxymethyl)-5,14,47,71,74-pentaisobutyl-17,23-diisopropyl-8,29,38,41,50-pentamethyl-53-(2-(methylthio)ethyl)-4,7,10,13,16,19,22,25,28,31,34,37,40,43,46,49,52,55,58,61,64,67,70,73,76-pentacosaoxo-3,6,9,12,15,18,21,24,27,30,33,36,39,42,45,48,51,54,57,60,63,66,69,72,75-pentacosaazaheptaheptacontanamido)-10,19-bis(4-aminobutyl)-7-((R)-1-hydroxyethyl)-13-(hydroxymethyl)-16-isobutyl-6,9,12,15,18,21-hexaoxo-1,2-dithia-5,8,11,14,17,20-hexaazacyclotricosane-4-carboxylic acid
Synonyms
Brevinin-2E-OG1 antimicrobial peptide; Brevinin-2-OA2; Gly-Leu-Leu-Asp-Thr-Phe-Lys-Asn-Met-Ala-Leu-Asn-Ala-Ala-Lys-Ser-Ala-Gly-Val-Ser-Val-Leu-Asn-Ala-Leu-Ser-Cys-Lys-Leu-Ser-Lys-Thr-Cys (Disulfide bridge: Cys27-Cys33)
Purity
≥96%
Sequence
GLLDTFKNMALNAAKSAGVSVLNALSCKLSKTC (Disulfide bridge: Cys27-Cys33)
Storage
Store at -20°C
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