Inquiry Basket
Cbz-Aib-Leu-OMe is a protected dipeptide used in peptide synthesis. The Cbz (Carbobenzyloxy) group protects the N-terminus of the α-aminoisobutyric acid (Aib) residue, preventing unwanted reactions during synthesis. Aib is a non-natural amino acid that induces helical structures in peptides due to its steric properties. Leu (Leucine) is the second amino acid in the sequence, known for its hydrophobic character, contributing to the overall structure and stability of the peptide. The OMe (methyl ester) group at the C-terminus indicates that the carboxyl group is esterified, which can be useful in strategies where further peptide extension or specific cleavage is required. This compound is employed to introduce both structural constraints and hydrophobic properties into peptides, enhancing their desired functional characteristics.
