Inquiry Basket
Cbz-Asp(OtBu)-Phe-Glu(OtBu)-OMe is a protected tripeptide used in peptide synthesis. The Cbz (Carbobenzyloxy) group protects the N-terminus of the aspartic acid (Asp) residue, preventing it from reacting during the synthesis process. Both the aspartic acid and glutamic acid (Glu) residues have their side chain carboxyl groups protected by OtBu (tert-butyl) groups, ensuring these groups remain unreactive until selective deprotection is required. Phe (Phenylalanine), the central amino acid in the sequence, adds hydrophobic and aromatic properties to the peptide. The OMe (methyl ester) at the C-terminus indicates that the carboxyl group of the glutamic acid is esterified, which can be useful for further synthetic modifications or coupling reactions. This compound is employed to introduce aspartic acid, phenylalanine, and glutamic acid into peptides, with controlled reactivity through specific protective groups.
