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Cbz-Ser(OtBu)-Asp(OtBu)-OMe is a protected dipeptide used in peptide synthesis. The Cbz (Carbobenzyloxy) group protects the N-terminus of the serine (Ser) residue, preventing it from reacting during synthesis. The hydroxyl group on serine is protected by a tBu (tert-butyl) group, which shields it until deprotection is required. The Asp (Aspartic acid) residue also has its side chain protected by a tBu group, ensuring that the side chain carboxyl group remains unreactive. The OMe (methyl ester) at the C-terminus indicates that the carboxyl group of the aspartic acid is esterified, which can facilitate further reactions or modifications. This compound is utilized to incorporate serine and aspartic acid into peptides, with specific protections in place to ensure controlled synthesis and functional modifications.
