Cbz-Ser(OtBu)-Asp(OtBu)-Tyr(OtBu)-Ser(OtBu)-OH
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Cbz-Ser(OtBu)-Asp(OtBu)-Tyr(OtBu)-Ser(OtBu)-OH

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Cbz-Ser(OtBu)-Asp(OtBu)-Tyr(OtBu)-Ser(OtBu)-OH is a protected tetrapeptide used in peptide synthesis. The Cbz (Carbobenzyloxy) group protects the N-terminus of the first serine (Ser) residue, preventing it from participating in undesired reactions during synthesis. The side chains of the serine (Ser), aspartic acid (Asp), and tyrosine (Tyr) residues are protected by OtBu (tert-butyl) groups, which shield the hydroxyl and carboxyl groups, ensuring that these functional groups remain inactive until selective deprotection. The final Ser residue has a free carboxyl group at the C-terminus, indicated by -OH, which allows for further modifications or coupling reactions. This peptide is designed to incorporate serine, aspartic acid, and tyrosine into peptide structures, with the protective groups ensuring controlled and efficient synthesis.

Category
Peptide Synthesis Reagents
Catalog number
BAT-016575
Molecular Formula
C43H64N4O12
Molecular Weight
829.00
Cbz-Ser(OtBu)-Asp(OtBu)-Tyr(OtBu)-Ser(OtBu)-OH
Synonyms
SDYS; N-((S)-2-((S)-2-((S)-2-(((Benzyloxy)carbonyl)amino)-3-(tert-butoxy)propanamido)-4-(tert-butoxy)-4-oxobutanamido)-3-(4-(tert-butoxy)phenyl)propanoyl)-O-(tert-butyl)-L-serine; Z-Ser(OtBu)-Asp(OtBu)-Tyr(OtBu)-Ser(OtBu)-OH; Cbz-Ser(tBu)-Asp(tBu)-Tyr(tBu)-Ser(tBu)-OH
Purity
≥97%
Sequence
Cbz-Ser(OtBu)-Asp(OtBu)-TyrOtBu)-Ser(OtBu)
InChI
InChI=1S/C43H64N4O12/c1-40(2,3)56-25-32(47-39(54)55-24-28-16-14-13-15-17-28)37(51)45-31(23-34(48)59-43(10,11)12)36(50)44-30(22-27-18-20-29(21-19-27)58-42(7,8)9)35(49)46-33(38(52)53)26-57-41(4,5)6/h13-21,30-33H,22-26H2,1-12H3,(H,44,50)(H,45,51)(H,46,49)(H,47,54)(H,52,53)/t30-,31-,32-,33-/m0/s1
InChI Key
GMKOQDSPWXEUIO-YRCZKMHPSA-N
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