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Cbz-Ser(tBu)-Ser(tBu)-OH is a protected dipeptide used in peptide synthesis. The Cbz (Carbobenzyloxy) group serves as a protective group for the N-terminus of the first serine residue, preventing unwanted reactions during the synthesis process. Each Ser (Serine) residue is protected at its hydroxyl side chain by a tBu (tert-butyl) group, ensuring that these reactive groups remain unaltered until selective deprotection is required. The -OH at the C-terminus indicates a free carboxyl group, allowing for further coupling reactions in the peptide chain. This compound is used to incorporate serine residues into peptides, with specific protections to facilitate precise and controlled synthesis.
