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Cbz-Thr(tBu)-Phe-OH is a protected dipeptide used in peptide synthesis. The Cbz (Carbobenzyloxy) group protects the N-terminus of the threonine residue, preventing reactions at this site during synthesis. The Thr (Threonine) residue is further protected at its hydroxyl side chain by a tBu (tert-butyl) group, ensuring the hydroxyl group remains unreactive until deprotection is desired. Phe (Phenylalanine) is the second amino acid, contributing aromatic character to the peptide. The -OH at the C-terminus signifies a free carboxyl group, which can participate in peptide bond formation. This compound is used to introduce threonine and phenylalanine into peptides with specific protective measures for controlled and selective synthesis.
