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Cbz-Tyr(OtBu)-Ser(OtBu)-OMe is a protected dipeptide used in peptide synthesis. The Cbz (Carbobenzyloxy) group protects the N-terminus of the tyrosine (Tyr) residue, preventing it from reacting during synthesis. The hydroxyl group of tyrosine is protected by an OtBu (tert-butyl) group, ensuring it remains unreactive until deprotection is necessary. The Ser (Serine) residue is similarly protected at its hydroxyl group by an OtBu group. The OMe (methyl ester) at the C-terminus indicates that the carboxyl group of the serine is esterified, facilitating further peptide coupling or modification. This compound is used to introduce tyrosine and serine into peptides while controlling the reactivity of their functional groups.
