β-Chloro-L-alanine methyl ester hydrochloride
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β-Chloro-L-alanine methyl ester hydrochloride

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Category
L-Amino Acids
Catalog number
BAT-005815
CAS number
17136-54-8
Molecular Formula
C4H8ClNO2·HCl
Molecular Weight
174.03
β-Chloro-L-alanine methyl ester hydrochloride
IUPAC Name
methyl (2R)-2-amino-3-chloropropanoate;hydrochloride
Synonyms
β-Chloro-L-Ala-OMe HCl
Appearance
White powder
Purity
≥ 98% (NMR)
Density
1.212 g/cm3
Melting Point
152-159 °C
Storage
Store at 2-8°C
InChI
InChI=1S/C4H8ClNO2.ClH/c1-8-4(7)3(6)2-5;/h3H,2,6H2,1H3;1H/t3-;/m0./s1
InChI Key
POPBCSXDEXRDSX-DFWYDOINSA-N
Canonical SMILES
COC(=O)C(CCl)N.Cl

β-Chloro-L-alanine methyl ester hydrochloride, a versatile biochemical reagent, finds application in various research and experimental contexts. Here are the key applications presented with high perplexity and burstiness:

Enzyme Inhibition Studies: Acting as an inhibitor in enzyme activity assays, β-Chloro-L-alanine methyl ester hydrochloride selectively targets pyridoxal phosphate-dependent enzymes. This property offers a unique avenue for scrutinizing enzyme function and kinetics, shedding light on the intricate mechanisms underlying enzyme catalysis. Furthermore, this application aids in the exploration of enzyme-based therapeutics, paving the way for novel treatment modalities.

Neuroscience Research: In the domain of neuroscience, this compound serves as a valuable tool for investigating neurotransmitter pathways. By selectively inhibiting specific aminotransferases, researchers can delve into the functions of key neurotransmitters such as gamma-aminobutyric acid (GABA) and glutamate. These studies are essential for unraveling the complexities of neural signaling and deciphering the pathophysiology of various neurological disorders, offering new insights into brain function.

Peptide Synthesis: Employed in peptide synthesis as a protected amino acid derivative, β-Chloro-L-alanine methyl ester hydrochloride aids in the creation of complex peptide structures by facilitating the introduction of chloro groups into peptide chains. This process is critical for the development of innovative therapeutic peptides and the exploration of protein interactions, opening avenues for groundbreaking discoveries in the field of peptide-based therapeutics.

Pharmacology Research: Playing a pivotal role in pharmacological investigations, this compound is utilized to assess the impacts of specific enzyme inhibition on metabolic and physiological processes. By elucidating its modulation of enzyme activity and metabolic pathways, researchers can glean valuable insights into drug metabolism and the design of next-generation pharmaceuticals. This comprehensive understanding contributes to the elucidation of pharmacokinetic profiles and the optimization of drug formulations, driving advancements in the realm of pharmacology.

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