β-Cyclopropyl-D-Ala-OH
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β-Cyclopropyl-D-Ala-OH

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Category
D-Amino Acids
Catalog number
BAT-005822
CAS number
121786-39-8
Molecular Formula
C6H11NO2
Molecular Weight
129.16
β-Cyclopropyl-D-Ala-OH
IUPAC Name
(2R)-2-amino-3-cyclopropylpropanoic acid
Synonyms
H-D-Ala(β-cyclopropyl)-OH
Appearance
Off-white powder
Purity
≥ 98%
Density
1.218g/cm3
Boiling Point
258°C at 760mmHg
Storage
Store at 2-8°C
InChI
InChI=1S/C6H11NO2/c7-5(6(8)9)3-4-1-2-4/h4-5H,1-3,7H2,(H,8,9)/t5-/m1/s1
InChI Key
XGUXJMWPVJQIHI-RXMQYKEDSA-N
Canonical SMILES
C1CC1CC(C(=O)O)N

β-Cyclopropyl-D-Ala-OH, a chiral building block, plays a pivotal role in peptide and pharmaceutical synthesis. Discover its diverse applications with heightened perplexity and burstiness:

Peptide Synthesis: As a crucial intermediate in peptide synthesis, β-Cyclopropyl-D-Ala-OH is instrumental in crafting intricate peptide structures. Its incorporation can introduce conformational constraints that bolster the stability and activity of the resultant peptides, making it an indispensable element in the creation of peptide-based drugs and biomolecules.

Drug Development: In the landscape of pharmaceutical research, β-Cyclopropyl-D-Ala-OH emerges as a key player in developing cutting-edge therapeutic agents. By integrating this compound into drug molecules, researchers can optimize the pharmacokinetics and pharmacodynamics of the drugs, potentially revolutionizing the realm of medicine with more potent and safer medications across a spectrum of diseases.

Enzyme Inhibition Studies: Delve into the world of enzyme inhibition and substrate specificity with β-Cyclopropyl-D-Ala-OH. Featuring a unique structure, this compound serves as a versatile mimic of natural substrates or inhibitors in enzymatic assays. Researchers harness its properties to unravel enzyme mechanisms and pinpoint potential inhibitors for therapeutic interventions, unveiling new pathways for drug discovery.

Chiral Ligand Development: Witness the significance of β-Cyclopropyl-D-Ala-OH as a cornerstone in chiral ligand design for asymmetric catalysis. These chiral ligands drive enantioselective reactions in organic synthesis, yielding optically pure compounds crucial in the production of chiral pharmaceuticals and fine chemicals. Explore the intricate world of chiral ligand development and its profound impact on the synthesis of essential compounds.

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