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Cys(Npys)-(D-Arg)9

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It is a peptide consisting of 9 D-arginine residues and one activated cysteine residue C(Npys), where Npys is 3-Nitro-2-pyridinesulfenyl group protects cysteine. This modification has been used to make the peptide suitable for conjugation and cell permeability studies as a carrier peptide. The S(Npys) group of this cysteine-containing 9R is capable of reacting selectively with the free thiol group of another cysteine-containing peptide to form an unsymmetrical disulfide bond.

Category

Functional Peptides

Catalog number

BAT-013308

Molecular Formula

C62H118N40O12S2

Molecular Weight

1679.99

Specification

Synonyms

H-Cys(Npys)-D-Arg-D-Arg-D-Arg-D-Arg-D-Arg-D-Arg-D-Arg-D-Arg-D-Arg-NH2; S-(3-nitropyridin-2-yl)sulfanyl-D-cysteinyl-D-arginyl-D-arginyl-D-arginyl-D-arginyl-D-arginyl-D-arginyl-D-arginyl-D-arginyl-D-argininamide

Appearance

Lyophilized Solid

Purity

≥95%

Density

1.6±0.1 g/cm3

Sequence

C(Npys)RRRRRRRRR-NH2 (all R amino acids are d-form amino acids)

Storage

Store at -20°C

Solubility

Soluble in water for a solution up to 3 mg/ml, otherwise acetonitrile is recommended. Avoid repeated freezing and thawing.