D-Alanine tert-butyl ester hydrochloride
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D-Alanine tert-butyl ester hydrochloride

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Category
D-Amino Acids
Catalog number
BAT-003474
CAS number
59531-86-1
Molecular Formula
C7H15NO2·HCl
Molecular Weight
181.70
D-Alanine tert-butyl ester hydrochloride
IUPAC Name
tert-butyl (2R)-2-aminopropanoate;hydrochloride
Synonyms
D-Ala-OtBu HCl; (R)-tert-Butyl 2-aminopropanoate hydrochloride
Appearance
White powder
Purity
≥ 98% (HPLC)
Melting Point
~ 200 °C
Storage
Store at 2-8°C
InChI
InChI=1S/C7H15NO2.ClH/c1-5(8)6(9)10-7(2,3)4;/h5H,8H2,1-4H3;1H/t5-;/m1./s1
InChI Key
WIQIWPPQGWGVHD-NUBCRITNSA-N
Canonical SMILES
CC(C(=O)OC(C)(C)C)N.Cl

D-Alanine tert-butyl ester hydrochloride, a derivative of the amino acid D-alanine, holds multiple applications within the bioscience industry. Here are the key applications presented with high perplexity and burstiness:

Peptide Synthesis: Serving as a fundamental block in peptide and protein synthesis, D-Alanine tert-butyl ester hydrochloride acts as an essential protecting group for D-alanine, ensuring precise reactions at designated molecular sites. This plays a crucial role in crafting intricate peptide chains with utmost accuracy and purity, crucial for advancing pharmaceutical research and drug innovation.

Chiral Synthesis: Embraced in asymmetric synthesis, this compound aids in generating chiral molecules with varied pharmaceutical applications. Functioning as a chiral auxiliary, D-Alanine tert-butyl ester hydrochloride directs the formation of specific stereoisomers. This is critical, as a molecule's chirality significantly impacts its biological activity and effectiveness, paving the way for tailored pharmaceutical solutions.

Pharmacology Research: Across the realm of antibiotic and therapeutic agent studies, D-Alanine tert-butyl ester hydrochloride finds its utility in exploring pharmacokinetics and metabolism of diverse compounds. Incorporating this compound into different formulations allows for a deeper understanding of how drugs interact at the molecular level, refining their design and enhancing therapeutic efficacy.

Biomolecular Engineering: Unlocking possibilities in biomolecular design, D-Alanine tert-butyl ester hydrochloride plays a pivotal role in crafting novel biomaterials for diverse engineering pursuits. By integrating this compound into polymer and nanoparticle matrices, researchers can engineer materials with specific biological functionalities. These advanced materials hold promise for applications in targeted drug delivery, biosensing technologies, and other cutting-edge medical innovations.

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