D-Aspartic acid dibenzyl ester 4-toluenesulfonate salt
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D-Aspartic acid dibenzyl ester 4-toluenesulfonate salt

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Category
D-Amino Acids
Catalog number
BAT-003480
CAS number
4079-64-5
Molecular Formula
C18H19NO4·C7H8O3S
Molecular Weight
485.60
D-Aspartic acid dibenzyl ester 4-toluenesulfonate salt
IUPAC Name
dibenzyl (2R)-2-aminobutanedioate;4-methylbenzenesulfonic acid
Synonyms
D-Asp(OBzl)-OBzl TosOH; d-aspartic acid dibenzyl ester tosylate
Appearance
White powder
Purity
≥ 98% (TLC)
Melting Point
155-158°C
Storage
Store at 2-8°C
InChI
InChI=1S/C18H19NO4.C7H8O3S/c19-16(18(21)23-13-15-9-5-2-6-10-15)11-17(20)22-12-14-7-3-1-4-8-14;1-6-2-4-7(5-3-6)11(8,9)10/h1-10,16H,11-13,19H2;2-5H,1H3,(H,8,9,10)/t16-;/m1./s1
InChI Key
HLMUYZYLPUHSNV-PKLMIRHRSA-N
Canonical SMILES
CC1=CC=C(C=C1)S(=O)(=O)O.C1=CC=C(C=C1)COC(=O)CC(C(=O)OCC2=CC=CC=C2)N

D-Aspartic acid dibenzyl ester 4-toluenesulfonate salt is a versatile chemical compound with diverse applications in bioscience and pharmaceutical research. Let’s explore its key applications with a high degree of perplexity and burstiness:

Peptide Synthesis: Utilizing D-Aspartic acid dibenzyl ester 4-toluenesulfonate salt as a pivotal component in peptide and peptidomimetic synthesis, researchers harness its ester structure for enhanced stability and seamless integration into evolving peptide chains during solid-phase synthesis. This refined methodology streamlines the generation of peptides for investigative and therapeutic pursuits, allowing for intricate peptide structures to be constructed with precision and efficiency.

Neurotransmitter Studies: Venturing into the intricacies of neuroscience, D-Aspartic acid emerges as a crucial neurotransmitter in the central nervous system, offering profound insights into neurotransmission and receptor functions. Scientists delve deep into the impact of D-Aspartic acid dibenzyl ester 4-toluenesulfonate salt on neurotransmitter pathways and synaptic plasticity, unveiling intricate details of neurological disorders and paving the way for innovative treatment approaches. This exploration of neurotransmitter dynamics opens new vistas for understanding and addressing complex neurological conditions.

Chiral Synthesis: Spearheading advancements in chiral chemistry, the D-enantiomer of aspartic acid within D-Aspartic acid dibenzyl ester 4-toluenesulfonate salt emerges as a cornerstone in asymmetric synthesis. Serving as a key precursor in creating optically active compounds, this application forms the foundation for synthesizing pharmaceuticals and fine chemicals where chirality dictates biological activity and drug efficacy. By harnessing the power of chiral synthesis, researchers unlock the potential for developing tailored pharmaceuticals with enhanced therapeutic outcomes and improved bioavailability.

Pharmaceutical Formulation: Unveiling innovative horizons in drug formulation, D-Aspartic acid dibenzyl ester 4-toluenesulfonate salt plays a pivotal role in crafting prodrugs to elevate drug delivery efficiency and bioavailability. By concealing the polar amino acid core with lipophilic ester groups, the compound optimizes the pharmacokinetic properties of therapeutic agents, revolutionizing drug absorption, distribution, and release kinetics. This strategic formulation approach empowers the design of pharmaceuticals with superior efficacy and precision, reshaping the landscape of pharmaceutical development and patient care.

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