D-Glutamic acid γ-benzyl ester α-amide hydrochloride
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D-Glutamic acid γ-benzyl ester α-amide hydrochloride

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Category
D-Amino Acids
Catalog number
BAT-003533
CAS number
18800-75-4
Molecular Formula
C12H16N2O3·HCl
Molecular Weight
272.50
D-Glutamic acid γ-benzyl ester α-amide hydrochloride
IUPAC Name
benzyl (4R)-4,5-diamino-5-oxopentanoate;hydrochloride
Synonyms
D-Glu(OBzl)-NH2 HCl; D-Isoglutamine benzyl ester HCl
Appearance
White crystalline powder
Purity
≥ 99% (HPLC)
Melting Point
180-187 °C
Storage
Store at 2-8 °C
InChI
InChI=1S/C12H16N2O3.ClH/c13-10(12(14)16)6-7-11(15)17-8-9-4-2-1-3-5-9;/h1-5,10H,6-8,13H2,(H2,14,16);1H/t10-;/m1./s1
InChI Key
HSXVFJRDTASLQJ-HNCPQSOCSA-N
Canonical SMILES
C1=CC=C(C=C1)COC(=O)CCC(C(=O)N)N.Cl

D-Glutamic acid γ-benzyl ester α-amide hydrochloride, a multifaceted chemical compound with diverse applications, holds prominence in various fields, particularly in pharmaceutical research and chemical synthesis.

Peptide Synthesis: In peptide synthesis, D-Glutamic acid γ-benzyl ester α-amide hydrochloride assumes a pivotal role in orchestrating the formation of specific peptide bonds. The ester group functions as a protective shield for the glutamic acid side chain, facilitating precise reactions. This compound enables the intricate assembly of complex peptides and proteins, catering to both research pursuits and therapeutic innovations.

Drug Development: Positioned as a versatile chemical intermediary, D-Glutamic acid γ-benzyl ester α-amide hydrochloride emerges as a significant player in the synthesis of pharmaceutical compounds. Researchers leverage its adaptable structure to explore its potential as a foundational component for drug candidates. By harnessing its reactivity and structural characteristics, novel therapeutics aimed at a spectrum of diseases begin to take form, laying the groundwork for cutting-edge medical advancements.

Bioconjugation Studies: Venturing into bioconjugation protocols, this compound enters the realm of linking bioactive molecules to carrier substrates, generating conjugates tailored for precise delivery or imaging purposes. With its reactive groups facilitating seamless coupling with other chemical entities, the resulting conjugates exhibit enhanced functionality.

Material Science: Embracing a role in material science, D-Glutamic acid γ-benzyl ester α-amide hydrochloride finds utility in modifying polymer properties or contributing as a constituent in the innovation of new materials. Its integration into polymer matrices introduces specific chemical functionalities or enhances the mechanical and thermal attributes of materials. This application acts as a catalyst for the development of advanced materials boasting specialized functionalities.

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